Neil Patrick Harris ........................ Peter Parker / Spider-Man
Lisa Loeb ...................................... Mary Jane "MJ" Watson
Ian Ziering ............................................. Harry Osborn
Ep: 1
Heroes and Villains
Also Starring: Edward Asner (Officer Barr), Victor Brandt (Oscorp Executive), Clancy Brown (Officer), Jane Lynch (Oscorp Executive), Karen Maruyama (Head Protestor), Suchin Pak (Alison Tomita), Harold Perrineau (Wyler / Turbo-Jet), Cree Summer (Jolenna / Professor Williams)
Written By: Morgan Gendel
Directed By: Tim Eldred
Ep: 2
Royal Scam
Also Starring: Keith David (Special Agent Mosely), Michael Clarke Duncan (Kingpin), Jamie Hanes (Fake Agent Roberts), Karen Maruyama (Flower Vendor), Suchin Pak (Alison Tomita), Keith Szarabajka (Kingpin's Henchman)
Written By: Rick Suvalle
Directed By: Vincent Edwards
Ep: 3
Law of the Jungle
Also Starring: Edward Asner (Officer Barr), Keith Carradine (J. Jonah Jameson), Kevin Michael Richardson (Security Guard), Rob Zombie (Dr. Curtis Connors / The Lizard)
Written By: Greg Johnson
Directed By: Audu Paden
Ep: 4
Sword of Shikata
Also Starring: Edward Asner (Officer Barr), Clancy Brown (Raymond / Henchmen), Gina Gershon (Shikata), James Horan (Henchman), John C. McGinley (Richard Damien)
Written By: Todd Felderstein & Morgan Gendel
Directed By: Brandon Vietti
Ep: 5
Keeping Secrets
Also Starring: Edward Asner (Officer Barr), Eve (Cheyenne Tate / The Talon), Jennifer Hale (Reporter)
Written By: Marsha Griffin
Directed By: Alan Caldwell
Ep: 6
Tight Squeeze
Also Starring: Susan Blu (CEO), Angelle Brooks (Indira "Indy" Daimonji), Keith Carradine (J. Jonah Jameson), Brendan Connolly (Aleksei), Ken Lerner (Boris), James Marsters (Sergei), Suchin Pak (Alison Tomita)
Written By: Morgan Gendel
Directed By: Audu Paden
Ep: 7
Head Over Heels
Also Starring: Angelle Brooks (Indira "Indy" Daimonji), Jeffrey Combs (Professor), Ethan Embry (Max Dillon), Rino Romano (Muang), Tara Strong (Christina)
Written By: Tracey Forbes
Directed By: Brandon Vietti
Ep: 8
The Party
Also Starring: Ethan Embry (Max Dillon / Electro), Jeff Fischer (Doug Reisman), Jennifer Hale (News Anouncer), Julie Nathanson (Sally Johnson), David Newsom (Gary), Rino Romano (Doug's Friend), Cree Summer (Professor Williams)
Story By: Brian Michael Bendis
Teleplay By: Brian Michael Bendis & Morgan Gendel & Marsha Griffin
Directed By: Audu Paden
Ep: 9
Flash Memory
Also Starring: Angelle Brooks (Indira "Indy" Daimonji), Keith Carradine (J. Jonah Jameson), Jeffrey Combs (Dr. Zellner), David DeLuise (Jack / Mack), Julie Nathanson (Sally Johnson), Suchin Pak (Alison Tomita), Devon Sawa (Flash Thompson)
Written By: Whip Lipsey & Scott Lipsey
Directed By: Tim Eldred
Ep: 10
Spider-Man Dis-Sabled
Also Starring: Xander Berkeley (Mayor), Angelle Brooks (Indira "Indy" Daimonji), Virginia Madsen (Silver Sable), Suchin Pak (Alison Tomita), Rino Romano (Buzzcut / Muang)
Also Starring: Angelle Brooks (Indira "Indy" Daimonji), Keith Carradine (J. Jonah Jameson), Michael Dorn (Kraven the Hunter), Kathy Griffin (Roxanne Gaines), Stan Lee (Frank Elson), Virginia Madsen (Silver Sable), James Marsters (Sergei), Suchin Pak (Alison Tomita), Jeremy Piven (Roland Gaines)
Written By: Morgan Gendel
Directed By: Alan Caldwell & Vincent Edwards & Audu Paden
Ep: 13
Mind Games, Part 2
Also Starring: Edward Asner (Officer Barr), Angelle Brooks (Indira "Indy" Daimonji), Keith Carradine (J. Jonah Jameson), Michael Dorn (Kraven the Hunter), Kathy Griffin (Roxanne Gaines), Suchin Pak (Alison Tomita), Jeremy Piven (Roland Gaines)
