Curriculum Vitae of Henry Jonker
Personals
Name: Jonker, Hendrik Richard André (Henry)
Abode: Epe, The Netherlands
Date and Place of birth: March 4, 1973, Apeldoorn, The Netherlands
Nationality: Dutch
Gender and civil status: Male, single
E-mail: 
Current occupation: Postdoc biomolecular NMR at the JW Goethe University in Frankfurt am Main
Education
1995-1997 Chemistry at Utrecht University (Analytical Molecular Spectrometry)
- Practical Training at the Unilever Research Laboratory in Vlaardingen
- Subject: Solid State NMR on semi-solid materials (Characterisation by Cross Relaxation NMR, T1-relaxation (solid-state) and DOSY)
- Option courses: Inorganic Chemistry, Structure Analysis, Spectroscopy
1991-1995 Analytical Chemistry at Rijkshogeschool IJselland in Deventer (HLO)
- Practical Training at the Mass Spectrometry Department of Utrecht University
- Subject: Mass Spectrometry on Peptidosulfonamids, Sequence analysis with Fast Atom Bombardment (FAB) Mass spectrometry
- Option courses: Multivariate Analysis, Spectrometric Identification, Novell Networks, Water purification and destillation
1985-1991 VWO, RSG "De Springborn" in Epe
- Dutch, English, Mathematics A and B, Physics, Chemistry, Biology
Experience
since 2004 Biomolecular NMR at the JW Goethe University in Frankfurt am Main
- Postdoc at the institute for organic chemistry and chemical biology
- Subjects: Study of ribosomal RNA-protein interactions by NMR
Structure calculation of several biomolecules; Deploying an eNMR infrastructure
1998-2003 Biomolecular NMR at the Bijvoet Center of Utrecht University
- Ph.D. employed by NWO (Dutch National Organisation for Scientific Research)
- Subject: NMR study of Protein-Protein Interaction in Transcriptional Activation
| 2008: |
Teacher at the EMBO world practical course NMR in Beijing |
| 2007,08: |
Teacher NMR assignment and structural calculations at OC practical |
| 2005: |
Teacher at the EMBO practical course NMR in Basel |
| 2004,05: |
Assistant at the Organic Chemistry practical for (bio)chemistry students |
| 2003: |
Parttime NMR spectroscopist at Unilever R&D (Vlaardingen) |
| 2001,02: |
Assistant at the Structural Biology course |
| 1999: |
Assistant at the practical Chemistry for first year chemistry students |
| 1993-96: |
Holiday job at Recreation centre "de Veldkamp" in Epe-Wissel |
| 1992: |
Laboratory worker at the Edese Beton Centrale BV in Apeldoorn |
Courses
| 2008: |
Practical course in Biomolecular Modelling (NCCR, Switzerland) |
| 2000: |
Advanced Course: From Data to Structures (BNRA, Utrecht/Nijmegen) |
|
Dynamic Presentation (Ludens) |
| 1999: |
Advanced Course: NMR Spectroscopy (BNRA, Utrecht/Nijmegen) |
|
Writing in English for Publication (James Boswell Institute) |
| 1997: |
NMR Spectroscopy, Chemometrics (Utrecht University) |
| 1996: |
Safety, Fire extinguish training (Hydro Agri, Vlaardingen) |
| 1995: |
Infrared Spectrometry, Mass Spectrometry (Utrecht University) |
Conferences, workshops and visits
| 2009: |
SFB-579 RNA-Ligand interactions (Arnoldshain-Schmitten), EU-NMR (Autrans) |
| 2008: |
e-NMR platform developer meetings (Florence, Padua) |
|
EU-NMR (Königstein), BMRZ workshop (Frankfurt, chair) |
|
EMBO world practical course NMR (Beijing, teacher) |
| 2007: |
EU-NMR & CA NMR-Life workshop (Florence), CA NMR-Life (Frankfurt) |
|
BMRZ workshop (Frankfurt, talk and organisation) |
|
Visit at the University Texas - Health Centre (San Antonio; talk and consultancy) |
|
e-NMR platform developer meeting (Utrecht), Bruker User Meeting (Ettlingen) |
| 2006: |
Bruker User Meeting (Ettlingen), CA NMR-Life workshop & Kaptein Symposium (Utrecht) |
|
International Conference on Magnetic Resonance in Biological Systems (Göttingen) |
| 2005: |
ESF Research Conference on NMR in Molecular Biology (Höör) |
|
NDDP meeting (Oberursel), GDCh NMR Symposium (Mainz) |
|
NMR-DG (Wageningen), SFB-579 RNA-Ligand interactions (Weilburg) |
| 2004: |
Bruker User Meeting (Ettlingen), ESBF Meeting (Frankfurt) |
|
NWO-CW Nucleic Acids (Lunteren) |
| 2003: |
NMR-DG (Groningen), LSF User Meeting (Oosterbeek) |
| 2002: |
Bijvoet Tutorial Symposium (Utrecht), NMR-DG (Vlaardingen) |
|
International Conference on Magnetic Resonance in Biological Systems (Toronto) |
|
Bruker Benelux Meeting (Eindhoven), NWO-CW Proteins (Lunteren) |
| 2001: |
NWO-CW Bio-Molecular Chemistry (Lunteren) |
|
NWO-CW Nucleic Acids (Lunteren), NWO-CW Proteins (Lunteren) |
|
LSF User Meeting (Frankfurt), Bruker Benelux User meeting (Brussels) |
| 2000: |
NWO-CW Bio-Molecular Chemistry (Lunteren), Bijvoet Tutorial Symposium (Utrecht) |
|
NWO-CW Nucleic Acids (Noordwijk), NWO-CW Proteins (Lunteren) |
|
International Conference on Magnetic Resonance in Biological Systems (Florence) |
|
Bruker Benelux User meeting (Den Bosch) |
| 1999: |
NWO-CW Proteins (Lunteren), NVBMB Meeting (AZU, Utrecht) |
|
Bijvoet Tutorial Symposium (Utrecht) |
| 1998: |
NWO-CW Proteins (Lunteren), NWO-CW Nucleic Acids (Lunteren) |
Publications
"The Human Cdc37-Hsp90 complex studied by heteronuclear NMR spectroscopy", Sreeramulu S, Jonker HRA, Langer T, Richter C, Lancaster CRD, Schwalbe H, JBC, 284 (2009), 3885-3896; abstract
"The high resolution NMR structure of Parvulustat (Z-2685) from Streptomyces parvulus FH-1641: Comparison with Tendamistat from Streptomyces tendae 4158", Rehm S, Han S, Hassani I, Sokocevic A, Jonker HRA, Engels JW, Schwalbe H, ChemBioChem, 10 (2009), 119-127; abstract
"Nuclear Magnetic Resonance (NMR) Spectroscopy: Overview of Applications in Chemical Biology", Nielsen G, Stadler M, Jonker HRA, Betz M, Schwalbe H, Wiley Encyclopedia of Chemical Biology, (2008), article online; abstract
"L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy", Jonker HRA, Ilin S, Grimm SK, Wöhnert J & Schwalbe H, Nucleic Acids Research, 35 (2007), 441-454; abstract
"Domain reorientation and induced fit upon RNA binding: solution structure and dynamics of ribosomal protein L11 from Thermotoga maritima", Ilin S, Hoskins A, Ohlenschläger O, Jonker HRA, Schwalbe H & Wöhnert J, ChemBioChem, 6 (2005), 1611-1618; abstract
"The intrinsically unstructured domain of PC4 modulates the activity of the structured core through inter- and intra-molecular interactions", Jonker HRA, Wechselberger RW, Boelens R, Kaptein R & Folkers GE, Biochemistry, 45 (2006), 5067-5081; abstract
"Gradual phosphorylation regulates PC4 coactivator function", Jonker HRA, Wechselberger RW, Pinkse M, Kaptein R & Folkers GE, FEBS, 273 (2006), 1430-1444; abstract
"Structural properties of the promiscuous VP16 activation domain", Jonker HRA, Wechselberger RW, Boelens R, Folkers GE & Kaptein R, Biochemistry, 44 (2005), 827-839; abstract
"Structural and functional studies on transcriptional activation - Interactions of the cofactor PC4 and activator VP16", Jonker HRA, Thesis Utrecht University, Faculty of Chemistry, ISBN 90-393-3545-1 (2003)
"Solid-like components in carbohydrate gels probed by NMR spectroscopy", van Duynhoven JPM, Kulik AS, Jonker HRA, Haverkamp J, Carbohydrate Polymers, 40 (1999), 211-219; abstract
Language Skills
Dutch, English and German, moderate French
Computer Skills
Operating Systems: DOS, Windows, Novell, UNIX, LINUX
Programming: (Quick)Basic, Turbo Pascal, dBASE IV, HTML, Tcl/Tk, Python
Statistics: SAS, Mathematica, Quattro, Excel, Lotus, Sirius
Chemistry: Chemwindows, Hyperchem, WinNMR, X-Win NMR & TopSpin (Bruker), vNMR (Varian), NMRPipe, Felix, Complement (Jeol), Rasmol, Molmol, Swiss PDB, PyMol, Sparky, Tensor, Pales, Module, CNS (X-Plor), Aria, Haddock, ....
Word processing and Presentation: Wordperfect Suite, Mìcrosoft Office
and many other software packages
References
Prof. Dr. Rob Kaptein (Utrecht University)
Prof. Dr. Rolf Boelens (Utrecht University)
Prof. Dr. Johan Haverkamp (Unilever Research Laboratory)
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