List of References
Thesis Henry Jonker: PC4 and VP16

1. Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., Doyle, M., FitzHugh, W., Funke, R., Gage, D., Harris, K., Heaford, A., Howland, J., Kann, L., Lehoczky, J., LeVine, R., McEwan, P., McKernan, K., Meldrim, J., Mesirov, J. P., Miranda, C., Morris, W., Naylor, J., Raymond, C., Rosetti, M., Santos, R., Sheridan, A., Sougnez, C., Stange-Thomann, N., Stojanovic, N., Subramanian, A., Wyman, D., Rogers, J., Sulston, J., Ainscough, R., Beck, S., Bentley, D., Burton, J., Clee, C., Carter, N., Coulson, A., Deadman, R., Deloukas, P., Dunham, A., Dunham, I., Durbin, R., French, L., Grafham, D., Gregory, S., Hubbard, T., Humphray, S., Hunt, A., Jones, M., Lloyd, C., McMurray, A., Matthews, L., Mercer, S., Milne, S., Mullikin, J. C., Mungall, A., Plumb, R., Ross, M., Shownkeen, R., Sims, S., Waterston, R. H., Wilson, R. K., Hillier, L. W., McPherson, J. D., Marra, M. A., Mardis, E. R., Fulton, L. A., Chinwalla, A. T., Pepin, K. H., Gish, W. R., Chissoe, S. L., Wendl, M. C., Delehaunty, K. D., Miner, T. L., Delehaunty, A., Kramer, J. B., Cook, L. L., Fulton, R. S., Johnson, D. L., Minx, P. J., Clifton, S. W., Hawkins, T., Branscomb, E., Predki, P., Richardson, P., Wenning, S., Slezak, T., Doggett, N., Cheng, J. F., Olsen, A., Lucas, S., Elkin, C., Uberbacher, E., Frazier, M., et al. (2001) Nature 409, 860-921.
2. Luger, K., Mader, A. W., Richmond, R. K., Sargent, D. F., and Richmond, T. J. (1997) Nature389, 251-60.
3. Davey, C. A., Sargent, D. F., Luger, K., Maeder, A. W., and Richmond, T. J. (2002) J Mol Biol319, 1097-113.
4. Belikov, S., and Karpov, V. (1998) FEBS Lett 441, 161-4.
5. Wu, J., and Grunstein, M. (2000) Trends Biochem Sci 25, 619-23.
6. Kornberg, R. D., and Lorch, Y. (1999) Cell 98, 285-94.
7. Berger, S. L. (2001) Oncogene 20, 3007-13.
8. Urnov, F. D., and Wolffe, A. P. (2001) Oncogene 20, 2991-3006.
9. Nowak, S. J., and Corces, V. G. (2000) Genes Dev 14, 3003-13.
10. Hsu, J. Y., Sun, Z. W., Li, X., Reuben, M., Tatchell, K., Bishop, D. K., Grushcow, J. M., Brame, C. J., Caldwell, J. A., Hunt, D. F., Lin, R., Smith, M. M., and Allis, C. D. (2000) Cell 102, 279-91.
11. Wei, Y., Yu, L., Bowen, J., Gorovsky, M. A., and Allis, C. D. (1999) Cell 97, 99-109.
12. Lo, W. S., Duggan, L., Tolga, N. C., Emre, Belotserkovskya, R., Lane, W. S., Shiekhattar, R., and Berger, S. L. (2001) Science 293, 1142-6.
13. Cheung, P., Tanner, K. G., Cheung, W. L., Sassone-Corsi, P., Denu, J. M., and Allis, C. D. (2000) Mol Cell 5, 905-15.
14. Rea, S., Eisenhaber, F., O'Carroll, D., Strahl, B. D., Sun, Z. W., Schmid, M., Opravil, S., Mechtler, K., Ponting, C. P., Allis, C. D., and Jenuwein, T. (2000) Nature 406, 593-9.
15. Rice, J. C., and Allis, C. D. (2001) Curr Opin Cell Biol 13, 263-73.
16. Stallcup, M. R. (2001) Oncogene 20, 3014-20.
17. Lachner, M., O'Carroll, D., Rea, S., Mechtler, K., and Jenuwein, T. (2001) Nature 410, 116-20.
18. Bannister, A. J., Zegerman, P., Partridge, J. F., Miska, E. A., Thomas, J. O., Allshire, R. C., and Kouzarides, T. (2001) Nature 410, 120-4.
19. Nakayama, J., Rice, J. C., Strahl, B. D., Allis, C. D., and Grewal, S. I. (2001) Science 292, 110-3.
20. Hampsey, M., and Reinberg, D. (2003) Cell 113, 429-32.
21. Robzyk, K., Recht, J., and Osley, M. A. (2000) Science 287, 501-4.
22. Pham, A. D., and Sauer, F. (2000) Science 289, 2357-60.
23. Varga-Weisz, P. (2001) Oncogene 20, 3076-85.
24. Kornberg, R. D., and Lorch, Y. (1999) Curr Opin Genet Dev 9, 148-51.
25. Aalfs, J. D., and Kingston, R. E. (2000) Trends Biochem Sci 25, 548-55.
26. Lorch, Y., Zhang, M., and Kornberg, R. D. (1999) Cell 96, 389-92.
27. Langst, G., Bonte, E. J., Corona, D. F., and Becker, P. B. (1999) Cell 97, 843-52.
28. Hamiche, A., Sandaltzopoulos, R., Gdula, D. A., and Wu, C. (1999) Cell 97, 833-42.
29. Kingston, R. E., Bunker, C. A., and Imbalzano, A. N. (1996) Genes Dev 10, 905-20.
30. Kornberg, R. D. (1999) Trends Cell Biol 9, M46-9.
31. Ptashne, M., and Gann, A. (1997) Nature 386, 569-77.
32. Orphanides, G., Lagrange, T., and Reinberg, D. (1996) Genes Dev 10, 2657-83.
33. Roeder, R. G. (1996) Trends Biochem Sci 21, 327-35.
34. Woychik, N. A., and Hampsey, M. (2002) Cell 108, 453-63.
35. Hampsey, M., and Reinberg, D. (1999) Curr Opin Genet Dev 9, 132-9.
36. Myers, L. C., and Kornberg, R. D. (2000) Annu Rev Biochem 69, 729-49.
37. Bjorklund, S., Almouzni, G., Davidson, I., Nightingale, K. P., and Weiss, K. (1999) Cell 96, 759-67.
38. Koleske, A. J., and Young, R. A. (1994) Nature 368, 466-9.
39. Myer, V. E., and Young, R. A. (1998) J Biol Chem 273, 27757-60.
40. Lemon, B., and Tjian, R. (2000) Genes Dev 14, 2551-69.
41. Nikolov, D. B., and Burley, S. K. (1997) Proc Natl Acad Sci U S A 94, 15-22.
42. Verrijzer, C. P., and Tjian, R. (1996) Trends Biochem Sci 21, 338-42.
43. Green, M. R. (2000) Trends Biochem Sci 25, 59-63.
44. Albright, S. R., and Tjian, R. (2000) Gene 242, 1-13.
45. Gangloff, Y. G., Romier, C., Thuault, S., Werten, S., and Davidson, I. (2001) Trends Biochem Sci 26, 250-7.
46. Cortes, P., Flores, O., and Reinberg, D. (1992) Mol Cell Biol 12, 413-21.
47. Zawel, L., and Reinberg, D. (1993) Prog Nucleic Acid Res Mol Biol 44, 67-108.
48. Berk, A. J. (1999) Curr Opin Cell Biol 11, 330-5.
49. Geiger, J. H., Hahn, S., Lee, S., and Sigler, P. B. (1996) Science 272, 830-6.
50. Tan, S., Hunziker, Y., Sargent, D. F., and Richmond, T. J. (1996) Nature 381, 127-51.
51. Zhu, W., Zeng, Q., Colangelo, C. M., Lewis, M., Summers, M. F., and Scott, R. A. (1996) Nat Struct Biol 3, 122-4.
52. Chen, H. T., Legault, P., Glushka, J., Omichinski, J. G., and Scott, R. A. (2000) Protein Sci 9, 1743-52.
53. Tsai, F. T., and Sigler, P. B. (2000) Embo J 19, 25-36.
54. Nikolov, D. B., Chen, H., Halay, E. D., Usheva, A. A., Hisatake, K., Lee, D. K., Roeder, R. G., and Burley, S. K. (1995) Nature 377, 119-28.
55. Bagby, S., Kim, S., Maldonado, E., Tong, K. I., Reinberg, D., and Ikura, M. (1995) Cell 82, 857-67.
56. Hayashi, F., Ishima, R., Liu, D., Tong, K. I., Kim, S., Reinberg, D., Bagby, S., and Ikura, M. (1998) Biochemistry 37, 7941-51.
57. Ha, I., Roberts, S., Maldonado, E., Sun, X., Kim, L. U., Green, M., and Reinberg, D. (1993) Genes Dev 7, 1021-32.
58. Tan, S., Conaway, R. C., and Conaway, J. W. (1995) Proc Natl Acad Sci U S A 92, 6042-6.
59. Gaiser, F., Tan, S., and Richmond, T. J. (2000) J Mol Biol 302, 1119-27.
60. Kamada, K., De Angelis, J., Roeder, R. G., and Burley, S. K. (2001) Proc Natl Acad Sci U S A98, 3115-20.
61. Nguyen, B. D., Chen, H. T., Kobor, M. S., Greenblatt, J., Legault, P., and Omichinski, J. G. (2003) Biochemistry 42, 1460-9.
62. Groft, C. M., Uljon, S. N., Wang, R., and Werner, M. H. (1998) Proc Natl Acad Sci U S A 95, 9117-22.
63. Kamada, K., Roeder, R. G., and Burley, S. K. (2003) Proc Natl Acad Sci U S A 100, 2296-9.
64. Holstege, F. C., van der Vliet, P. C., and Timmers, H. Th. M. (1996) Embo J 15, 1666-77.
65. Okuda, M., Watanabe, Y., Okamura, H., Hanaoka, F., Ohkuma, Y., and Nishimura, Y. (2000) Embo J 19, 1346-56.
66. Coulombe, B., and Burton, Z. F. (1999) Microbiol Mol Biol Rev 63, 457-78.
67. Robert, F., Douziech, M., Forget, D., Egly, J. M., Greenblatt, J., Burton, Z. F., and Coulombe, B. (1998) Mol Cell 2, 341-51.
68. Conaway, J. W., Shilatifard, A., Dvir, A., and Conaway, R. C. (2000) Trends Biochem Sci 25, 375-80.
69. Dvir, A., Conaway, J. W., and Conaway, R. C. (2001) Curr Opin Genet Dev 11, 209-14.
70. Seroz, T., Hwang, J. R., Moncollin, V., and Egly, J. M. (1995) Curr Opin Genet Dev 5, 217-21.
71. Egly, J. M. (2001) FEBS Lett 498, 124-8.
72. Svejstrup, J. Q., Wang, Z., Feaver, W. J., Wu, X., Bushnell, D. A., Donahue, T. F., Friedberg, E. C., and Kornberg, R. D. (1995) Cell 80, 21-8.
73. Schaeffer, L., Roy, R., Humbert, S., Moncollin, V., Vermeulen, W., Hoeijmakers, J. H., Chambon, P., and Egly, J. M. (1993) Science 260, 58-63.
74. Lu, H., Zawel, L., Fisher, L., Egly, J. M., and Reinberg, D. (1992) Nature 358, 641-5.
75. Dahmus, M. E. (1996) J Biol Chem 271, 19009-12.
76. Schneider, E., Kartarius, S., Schuster, N., and Montenarh, M. (2002) Oncogene 21, 5031-7.
77. Akoulitchev, S., Chuikov, S., and Reinberg, D. (2000) Nature 407, 102-6.
78. Douziech, M., Coin, F., Chipoulet, J. M., Arai, Y., Ohkuma, Y., Egly, J. M., and Coulombe, B. (2000) Mol Cell Biol 20, 8168-77.
79. Kim, T. K., Ebright, R. H., and Reinberg, D. (2000) Science 288, 1418-22.
80. Schultz, P., Fribourg, S., Poterszman, A., Mallouh, V., Moras, D., and Egly, J. M. (2000) Cell102, 599-607.
81. Chang, W. H., and Kornberg, R. D. (2000) Cell 102, 609-13.
82. Fribourg, S., Kellenberger, E., Rogniaux, H., Poterszman, A., Van Dorsselaer, A., Thierry, J. C., Egly, J. M., Moras, D., and Kieffer, B. (2000) J Biol Chem 275, 31963-71.
83. Gervais, V., Busso, D., Wasielewski, E., Poterszman, A., Egly, J. M., Thierry, J. C., and Kieffer, B. (2001) J Biol Chem 276, 7457-64.
84. Kornberg, R. D. (2001) Biol Chem 382, 1103-7.
85. Murray, S., Udupa, R., Yao, S., Hartzog, G., and Prelich, G. (2001) Mol Cell Biol 21, 4089-96.
86. Cramer, P., Bushnell, D. A., and Kornberg, R. D. (2001) Science 292, 1863-76.
87. Gnatt, A. L., Cramer, P., Fu, J., Bushnell, D. A., and Kornberg, R. D. (2001) Science 292, 1876-82.
88. Kolodziej, P. A., Woychik, N., Liao, S. M., and Young, R. A. (1990) Mol Cell Biol 10, 1915-20.
89. Kayukawa, K., Makino, Y., Yogosawa, S., and Tamura, T. (1999) Gene 234, 139-47.
90. Klug, A. (2001) Science 292, 1844-6.
91. Armache, K. J., Kettenberger, H., and Cramer, P. (2003) Proc Natl Acad Sci U S A 100, 6964-8.
92. Todone, F., Brick, P., Werner, F., Weinzierl, R. O., and Onesti, S. (2001) Mol Cell 8, 1137-43.
93. Orlicky, S. M., Tran, P. T., Sayre, M. H., and Edwards, A. M. (2001) J Biol Chem 276, 10097-102.
94. Orphanides, G., and Reinberg, D. (2000) Nature 407, 471-5.
95. Fry, C. J., and Peterson, C. L. (2002) Science 295, 1847-8.
96. Triezenberg, S. J. (1995) Curr Opin Genet Dev 5, 190-6.
97. Mitchell, P. J., and Tjian, R. (1989) Science 245, 371-8.
98. Cress, W. D., and Triezenberg, S. J. (1991) Science 251, 87-90.
99. Regier, J. L., Shen, F., and Triezenberg, S. J. (1993) Proc Natl Acad Sci U S A 90, 883-7.
100. Blair, W. S., Bogerd, H. P., Madore, S. J., and Cullen, B. R. (1994) Mol Cell Biol 14, 7226-34.
101. Lin, J., Chen, J., Elenbaas, B., and Levine, A. J. (1994) Genes Dev 8, 1235-46.
102. Jackson, B. M., Drysdale, C. M., Natarajan, K., and Hinnebusch, A. G. (1996) Mol Cell Biol 16, 5557-71.
103. Iniguez-Lluhi, J. A., Lou, D. Y., and Yamamoto, K. R. (1997) J Biol Chem 272, 4149-56.
104. Almlof, T., Gustafsson, J. A., and Wright, A. P. (1997) Mol Cell Biol 17, 934-45.
105. Tompa, P. (2002) Trends Biochem Sci 27, 527-33.
106. Wright, P. E., and Dyson, H. J. (1999) J Mol Biol 293, 321-31.
107. Uesugi, M., Nyanguile, O., Lu, H., Levine, A. J., and Verdine, G. L. (1997) Science 277, 1310-3.
108. Kussie, P. H., Gorina, S., Marechal, V., Elenbaas, B., Moreau, J., Levine, A. J., and Pavletich, N. P. (1996) Science 274, 948-53.
109. Uesugi, M., and Verdine, G. L. (1999) Proc Natl Acad Sci U S A 96, 14801-6.
110. Radhakrishnan, I., Perez-Alvarado, G. C., Parker, D., Dyson, H. J., Montminy, M. R., and Wright, P. E. (1997) Cell 91, 741-52.
111. Zor, T., Mayr, B. M., Dyson, H. J., Montminy, M. R., and Wright, P. E. (2002) J Biol Chem 277, 42241-8.
112. Harris, S. F., and Botchan, M. R. (1999) Science 284, 1673-7.
113. Nagadoi, A., Nakazawa, K., Uda, H., Okuno, K., Maekawa, T., Ishii, S., and Nishimura, Y. (1999) J Mol Biol 287, 593-607.
114. Cho, H. S., Liu, C. W., Damberger, F. F., Pelton, J. G., Nelson, H. C., and Wemmer, D. E. (1996) Protein Sci 5, 262-9.
115. Lee, H., Mok, K. H., Muhandiram, R., Park, K. H., Suk, J. E., Kim, D. H., Chang, J., Sung, Y. C., Choi, K. Y., and Han, K. H. (2000) J Biol Chem 275, 29426-32.
116. Rudiger, S., Freund, S. M., Veprintsev, D. B., and Fersht, A. R. (2002) Proc Natl Acad Sci U S A99, 11085-90.
117. Parker, D., Rivera, M., Zor, T., Henrion-Caude, A., Radhakrishnan, I., Kumar, A., Shapiro, L., Wright, P., Montminy, M., and Brindle, P. K. (1999) Mol Cell Biol 19, 5601-7.
118. Hermann, S., Berndt, K. D., and Wright, A. P. (2001) J Biol Chem 276, 40127-32.
119. Weir, J. P. (2001) Gene 271, 117-30.
120. Wysocka, J., and Herr, W. (2003) Trends Biochem Sci 28, 294-304.
121. Campbell, M. E., Palfreyman, J. W., and Preston, C. M. (1984) J Mol Biol 180, 1-19.
122. Triezenberg, S. J., Kingsbury, R. C., and McKnight, S. L. (1988) Genes Dev 2, 718-29.
123. Hayes, S., and O'Hare, P. (1993) J Virol 67, 852-62.
124. Liu, Y., Gong, W., Huang, C. C., Herr, W., and Cheng, X. (1999) Genes Dev 13, 1692-703.
125. Herr, W. (1998) Cold Spring Harb Symp Quant Biol 63, 599-607.
126. Luciano, R. L., and Wilson, A. C. (2002) Proc Natl Acad Sci U S A 99, 13403-8.
127. Ranish, J. A., Yudkovsky, N., and Hahn, S. (1999) Genes Dev 13, 49-63.
128. Jiang, Y., Triezenberg, S. J., and Gralla, J. D. (1994) J Biol Chem 269, 5505-8.
129. Stringer, K. F., Ingles, C. J., and Greenblatt, J. (1990) Nature 345, 783-6.
130. Kobayashi, N., Boyer, T. G., and Berk, A. J. (1995) Mol Cell Biol 15, 6465-73.
131. Kobayashi, N., Horn, P. J., Sullivan, S. M., Triezenberg, S. J., Boyer, T. G., and Berk, A. J. (1998) Mol Cell Biol 18, 4023-31.
132. Lin, Y. S., Ha, I., Maldonado, E., Reinberg, D., and Green, M. R. (1991) Nature 353, 569-71.
133. Zhu, H., Joliot, V., and Prywes, R. (1994) J Biol Chem 269, 3489-97.
134. Xiao, H., Pearson, A., Coulombe, B., Truant, R., Zhang, S., Regier, J. L., Triezenberg, S. J., Reinberg, D., Flores, O., Ingles, C. J., and et al. (1994) Mol Cell Biol 14, 7013-24.
135. Goodrich, J. A., Hoey, T., Thut, C. J., Admon, A., and Tjian, R. (1993) Cell 75, 519-30.
136. Klemm, R. D., Goodrich, J. A., Zhou, S., and Tjian, R. (1995) Proc Natl Acad Sci U S A 92, 5788-92.
137. Ito, M., Yuan, C. X., Malik, S., Gu, W., Fondell, J. D., Yamamura, S., Fu, Z. Y., Zhang, X., Qin, J., and Roeder, R. G. (1999) Mol Cell 3, 361-70.
138. Naar, A. M., Beaurang, P. A., Zhou, S., Abraham, S., Solomon, W., and Tjian, R. (1999) Nature398, 828-32.
139. Malik, S., and Roeder, R. G. (2000) Trends Biochem Sci 25, 277-83.
140. Xiao, H., Tao, Y., and Roeder, R. G. (1999) J Biol Chem 274, 3937-40.
141. Kretzschmar, M., Kaiser, K., Lottspeich, F., and Meisterernst, M. (1994) Cell 78, 525-34.
142. Ge, H., and Roeder, R. G. (1994) Cell 78, 513-23.
143. Hardy, S., Brand, M., Mittler, G., Yanagisawa, J., Kato, S., Meisterernst, M., and Tora, L. (2002) J Biol Chem 277, 32875-82.
144. Ikeda, K., Stuehler, T., and Meisterernst, M. (2002) Genes Cells 7, 49-58.
145. Kraus, W. L., Manning, E. T., and Kadonaga, J. T. (1999) Mol Cell Biol 19, 8123-35.
146. Kundu, T. K., Palhan, V. B., Wang, Z., An, W., Cole, P. A., and Roeder, R. G. (2000) Mol Cell 6, 551-61.
147. Kays, A. R., and Schepartz, A. (2002) Biochemistry 41, 3147-55.
148. Nishikawa, J., Kokubo, T., Horikoshi, M., Roeder, R. G., and Nakatani, Y. (1997) Proc Natl Acad Sci U S A 94, 85-90.
149. Tumbar, T., Sudlow, G., and Belmont, A. S. (1999) J Cell Biol 145, 1341-54.
150. Tumbar, T., and Belmont, A. S. (2001) Nat Cell Biol 3, 134-9.
151. Neely, K. E., Hassan, A. H., Brown, C. E., Howe, L., and Workman, J. L. (2002) Mol Cell Biol22, 1615-25.
152. Brown, C. E., Howe, L., Sousa, K., Alley, S. C., Carrozza, M. J., Tan, S., and Workman, J. L. (2001) Science 292, 2333-7.
153. Memedula, S., and Belmont, A. S. (2003) Curr Biol 13, 241-6.
154. Seipel, K., Georgiev, O., and Schaffner, W. (1992) Embo J 11, 4961-8.
155. Walker, S., Greaves, R., and O'Hare, P. (1993) Mol Cell Biol 13, 5233-44.
156. Seipel, K., Georgiev, O., and Schaffner, W. (1994) Biol Chem Hoppe Seyler 375, 463-70.
157. Sullivan, S. M., Horn, P. J., Olson, V. A., Koop, A. H., Niu, W., Ebright, R. H., and Triezenberg, S. J. (1998) Nucleic Acids Res 26, 4487-96.
158. Lin, Y. S., and Green, M. R. (1991) Cell 64, 971-81.
159. Ingles, C. J., Shales, M., Cress, W. D., Triezenberg, S. J., and Greenblatt, J. (1991) Nature 351, 588-90.
160. O'Hare, P., and Williams, G. (1992) Biochemistry 31, 4150-6.
161. Grossmann, J. G., Sharff, A. J., O'Hare, P., and Luisi, B. (2001) Biochemistry 40, 6267-74.
162. Shen, F., Triezenberg, S. J., Hensley, P., Porter, D., and Knutson, J. R. (1996) J Biol Chem271, 4827-37.
163. Dion, V., and Coulombe, B. (2003) J Biol Chem 278, 11495-501.
164. Perissi, V., Dasen, J. S., Kurokawa, R., Wang, Z., Korzus, E., Rose, D. W., Glass, C. K., and Rosenfeld, M. G. (1999) Proc Natl Acad Sci U S A 96, 3652-7.
165. Gu, W., and Roeder, R. G. (1997) Cell 90, 595-606.
166. Dornan, D., Shimizu, H., Perkins, N. D., and Hupp, T. R. (2003) J Biol Chem 278, 13431-41.
167. Kumar, B. R., Swaminathan, V., Banerjee, S., and Kundu, T. K. (2001) J Biol Chem 276, 16804-9.
168. Muscat, G. E., Burke, L. J., and Downes, M. (1998) Nucleic Acids Res 26, 2899-907.
169. Wong, C. W., and Privalsky, M. L. (1998) Mol Cell Biol 18, 5500-10.
170. Guenther, M. G., Barak, O., and Lazar, M. A. (2001) Mol Cell Biol 21, 6091-101.
171. Kaiser, K., and Meisterernst, M. (1996) Trends Biochem Sci 21, 342-5.
172. Bjorklund, S., and Kim, Y. J. (1996) Trends Biochem Sci 21, 335-7.
173. Rachez, C., and Freedman, L. P. (2001) Curr Opin Cell Biol 13, 274-80.
174. Wang, G., Cantin, G. T., Stevens, J. L., and Berk, A. J. (2001) Mol Cell Biol 21, 4604-13.
175. Asturias, F. J., Jiang, Y. W., Myers, L. C., Gustafsson, C. M., and Kornberg, R. D. (1999) Science 283, 985-7.
176. Dotson, M. R., Yuan, C. X., Roeder, R. G., Myers, L. C., Gustafsson, C. M., Jiang, Y. W., Li, Y., Kornberg, R. D., and Asturias, F. J. (2000) Proc Natl Acad Sci U S A 97, 14307-10.
177. Meisterernst, M., Roy, A. L., Lieu, H. M., and Roeder, R. G. (1991) Cell 66, 981-93.
178. Ge, H., and Roeder, R. G. (1994) J Biol Chem 269, 17136-40.
179. Kretzschmar, M., Meisterernst, M., and Roeder, R. G. (1993) Proc Natl Acad Sci U S A 90, 11508-12.
180. Malik, S., Guermah, M., and Roeder, R. G. (1998) Proc Natl Acad Sci U S A 95, 2192-7.
181. Merino, A., Madden, K. R., Lane, W. S., Champoux, J. J., and Reinberg, D. (1993) Nature 365, 227-32.
182. Kamada, K., Shu, F., Chen, H., Malik, S., Stelzer, G., Roeder, R. G., Meisterernst, M., and Burley, S. K. (2001) Cell 106, 71-81.
183. Nolte, R. T., Wisely, G. B., Westin, S., Cobb, J. E., Lambert, M. H., Kurokawa, R., Rosenfeld, M. G., Willson, T. M., Glass, C. K., and Milburn, M. V. (1998) Nature 395, 137-43.
184. Darimont, B. D., Wagner, R. L., Apriletti, J. W., Stallcup, M. R., Kushner, P. J., Baxter, J. D., Fletterick, R. J., and Yamamoto, K. R. (1998) Genes Dev 12, 3343-56.
185. Shiau, A. K., Barstad, D., Loria, P. M., Cheng, L., Kushner, P. J., Agard, D. A., and Greene, G. L. (1998) Cell 95, 927-37.
186. Liu, D., Ishima, R., Tong, K. I., Bagby, S., Kokubo, T., Muhandiram, D. R., Kay, L. E., Nakatani, Y., and Ikura, M. (1998) Cell 94, 573-83.
187. Chang, J. F., Phillips, K., Lundback, T., Gstaiger, M., Ladbury, J. E., and Luisi, B. (1999) J Mol Biol 288, 941-52.
188. Dunker, A. K., Lawson, J. D., Brown, C. J., Williams, R. M., Romero, P., Oh, J. S., Oldfield, C. J., Campen, A. M., Ratliff, C. M., Hipps, K. W., Ausio, J., Nissen, M. S., Reeves, R., Kang, C., Kissinger, C. R., Bailey, R. W., Griswold, M. D., Chiu, W., Garner, E. C., and Obradovic, Z. (2001) J Mol Graph Model 19, 26-59.
189. Dunker, A. K., Brown, C. J., Lawson, J. D., Iakoucheva, L. M., and Obradovic, Z. (2002) Biochemistry 41, 6573-82.
190. Soma, G., Kitahara, N., and Andoh, T. (1984) Biochem Biophys Res Commun 124, 164-71.
191. Ballard, D. W., Philbrick, W. M., and Bothwell, A. L. (1988) J Biol Chem 263, 8450-7.
192. Kaiser, K., Stelzer, G., and Meisterernst, M. (1995) Embo J 14, 3520-7.
193. Henry, N. L., Bushnell, D. A., and Kornberg, R. D. (1996) J Biol Chem 271, 21842-7.
194. Knaus, R., Pollock, R., and Guarente, L. (1996) Embo J 15, 1933-40.
195. Brandsen, J., Werten, S., van der Vliet, P. C., Meisterernst, M., Kroon, J., and Gros, P. (1997) Nat Struct Biol 4, 900-3.
196. Werten, S., Wechselberger, R., Boelens, R., van der Vliet, P. C., and Kaptein, R. (1999) J Biol Chem 274, 3693-9.
197. Bochkarev, A., Pfuetzner, R. A., Edwards, A. M., and Frappier, L. (1997) Nature 385, 176-81.
198. Werten, S., Langen, F. W., van Schaik, R., Timmers, H. Th. M., Meisterernst, M., and van der Vliet, P. C. (1998) J Mol Biol 276, 367-77.
199. Pan, Z. Q., Ge, H., Amin, A. A., and Hurwitz, J. (1996) J Biol Chem 271, 22111-6.
200. Jacobs, D. M., Lipton, A. S., Isern, N. G., Daughdrill, G. W., Lowry, D. F., Gomes, X., and Wold, M. S. (1999) J Biomol NMR 14, 321-31.
201. Binz, S. K., Lao, Y., Lowry, D. F., and Wold, M. S. (2003) J Biol Chem.
202. Ge, H., Zhao, Y., Chait, B. T., and Roeder, R. G. (1994) Proc Natl Acad Sci U S A 91, 12691-5.
203. Schang, L. M., Hwang, G. J., Dynlacht, B. D., Speicher, D. W., Bantly, A., Schaffer, P. A., Shilatifard, A., Ge, H., and Shiekhattar, R. (2000) J Biol Chem 275, 6071-4.
204. Soengas, M. S., Gutierrez, C., and Salas, M. (1995) J Mol Biol 253, 517-29.
205. Dekker, J., Kanellopoulos, P. N., Loonstra, A. K., van Oosterhout, J. A., Leonard, K., Tucker, P. A., and van der Vliet, P. C. (1997) Embo J 16, 1455-63.
206. Wu, S. Y., and Chiang, C. M. (1998) J Biol Chem 273, 12492-8.
207. Werten, S., Stelzer, G., Goppelt, A., Langen, F. M., Gros, P., Timmers, H. Th. M., Van der Vliet, P. C., and Meisterernst, M. (1998) Embo J 17, 5103-11.
208. Kershnar, E., Wu, S. Y., and Chiang, C. M. (1998) J Biol Chem 273, 34444-53.
209. Wu, S. Y., Kershnar, E., and Chiang, C. M. (1998) Embo J 17, 4478-90.
210. Fukuda, A., Tokonabe, S., Hamada, M., Matsumoto, M., Tsukui, T., Nogi, Y., and Hisatake, K. (2003) J Biol Chem.
211. Bohm, M., Kirch, H., Otto, T., Rubben, H., and Wieland, I. (1997) Int J Cancer 74, 291-5.
212. Wieland, I., Bohm, M., Arden, K. C., Ammermuller, T., Bogatz, S., Viars, C. S., and Rajewsky, M. F. (1996) Oncogene 12, 97-102.
213. Kannan, P., and Tainsky, M. A. (1999) Mol Cell Biol 19, 899-908.
214. Haile, D. T., and Parvin, J. D. (1999) J Biol Chem 274, 2113-7.
215. Holloway, A. F., Occhiodoro, F., Mittler, G., Meisterernst, M., and Shannon, M. F. (2000) J Biol Chem 275, 21668-77.
216. Ge, H., Si, Y., and Roeder, R. G. (1998) Embo J 17, 6723-9.
217. Calvo, O., and Manley, J. L. (2001) Mol Cell 7, 1013-23.
218. Wang, Z., and Roeder, R. G. (1998) Mol Cell 1, 749-57.
219. Gu, W., Malik, S., Ito, M., Yuan, C. X., Fondell, J. D., Zhang, X., Martinez, E., Qin, J., and Roeder, R. G. (1999) Mol Cell 3, 97-108.
220. Currie, R. A. (1998) J Biol Chem 273, 18220-9.
221. Fondell, J. D., Guermah, M., Malik, S., and Roeder, R. G. (1999) Proc Natl Acad Sci U S A 96, 1959-64.
222. Luo, Y., Ge, H., Stevens, S., Xiao, H., and Roeder, R. G. (1998) Mol Cell Biol 18, 3803-10.
223. Muramatsu, S., Handa, A., Kajigaya, S., and Brown, K. E. (1998) J Gen Virol 79 ( Pt 9), 2157-61.
224. Weger, S., Wendland, M., Kleinschmidt, J. A., and Heilbronn, R. (1999) J Virol 73, 260-9.
225. Wu, S. Y., and Chiang, C. M. (2001) J Biol Chem 276, 34235-43.
226. Guo, H., Cai, C. Q., and Kuo, P. C. (2002) J Biol Chem 277, 5054-60.
227. Cramer, P., Bushnell, D. A., Fu, J., Gnatt, A. L., Maier-Davis, B., Thompson, N. E., Burgess, R. R., Edwards, A. M., David, P. R., and Kornberg, R. D. (2000) Science 288, 640-9.
228. Struhl, K. (1996) Cell 84, 179-82.
229. Burley, S. K., and Roeder, R. G. (1996) Annu Rev Biochem 65, 769-99.
230. Lacoste, J., Codani-Simonart, S., Best-Belpomme, M., and Peronnet, F. (1995) Nucleic Acids Res 23, 5073-9.
231. Folkers, G. E., and van der Saag, P. T. (1995) Mol Cell Biol 15, 5868-78.
232. Cavanagh, J., Fairbrother, W. J., Palmer III, A. G., and Skelton, N. J. (1996) Protein NMR Spectroscopy, Academic Press, San Diego, CA.
233. Mulder, F. A. A., de Graaf, R. A., Kaptein, R., and Boelens, R. (1998) J Magn Reson 131, 351-7.
234. Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) J Biomol NMR6, 277-93.
235. Sadowski, I., Ma, J., Triezenberg, S., and Ptashne, M. (1988) Nature 335, 563-4.
236. Lillie, J. W., and Green, M. R. (1989) Nature 338, 39-44.
237. Folkers, G. E., van der Leede, B. J., and van der Saag, P. T. (1993) Mol Endocrinol 7, 616-27.
238. Wang, Y., and Jardetzky, O. (2002) Protein Sci 11, 852-61.
239. Wishart, D. S., and Sykes, B. D. (1994) J Biomol NMR 4, 171-80.
240. Cornilescu, G., Delaglio, F., and Bax, A. (1999) J Biomol NMR 13, 289-302.
241. Baxter, N. J., and Williamson, M. P. (1997) J Biomol NMR 9, 359-69.
242. Koradi, R., Billeter, M., and Wuthrich, K. (1996) J Mol Graph. 14, 51-5, 29-32.
243. Vis, H., Boelens, R., Mariani, M., Stroop, R., Vorgias, C. E., Wilson, K. S., and Kaptein, R. (1994) Biochemistry 33, 14858-70.
244. Kobor, M. S., and Greenblatt, J. (2002) Biochim Biophys Acta 1577, 261-275.
245. Dahmus, M. E. (1994) Prog Nucleic Acid Res Mol Biol 48, 143-79.
246. Cadena, D. L., and Dahmus, M. E. (1987) J Biol Chem 262, 12468-74.
247. Bensaude, O., Bonnet, F., Casse, C., Dubois, M. F., Nguyen, V. T., and Palancade, B. (1999) Biochem Cell Biol 77, 249-55.
248. Karin, M., and Hunter, T. (1995) Curr Biol 5, 747-57.
249. Hill, C. S., and Treisman, R. (1995) Cell 80, 199-211.
250. Brivanlou, A. H., and Darnell, J. E., Jr. (2002) Science 295, 813-8.
251. Bienkiewicz, E. A., and Lumb, K. J. (1999) J Biomol NMR 15, 203-6.
252. Hathaway, G. M., and Traugh, J. A. (1983) Methods Enzymol 99, 317-31.
253. Pinna, L. A. (1990) Biochim Biophys Acta 1054, 267-84.
254. van Breukelen, B., Kanellopoulos, P. N., Tucker, P. A., and van der Vliet, P. C. (2000) J Biol Chem 275, 40897-903.
255. Tucker, P. A., Tsernoglou, D., Tucker, A. D., Coenjaerts, F. E., Leenders, H., and van der Vliet, P. C. (1994) Embo J 13, 2994-3002.
256. Choy, B., and Green, M. R. (1993) Nature 366, 531-6.
257. Tjian, R., and Maniatis, T. (1994) Cell 77, 5-8.
258. Bentley, D. L. (1995) Curr Opin Genet Dev 5, 210-6.
259. Donaldson, L., and Capone, J. P. (1992) J Biol Chem 267, 1411-4.
260. Tanaka, M. (1996) Proc Natl Acad Sci U S A 93, 4311-5.
261. Uversky, V. N. (2002) Protein Sci 11, 739-56.
262. Ptitsyn, O. B., and Uversky, V. N. (1994) FEBS Lett 341, 15-8.
263. Morelli, X. J., Palma, P. N., Guerlesquin, F., and Rigby, A. C. (2001) Protein Sci 10, 2131-7.
264. Palma, P. N., Krippahl, L., Wampler, J. E., and Moura, J. J. (2000) Proteins 39, 372-84.
265. Guex, N., and Peitsch, M. C. (1997) Electrophoresis 18, 2714-23.
266. van Gunsteren, W. F., Billeter, S. R., Eising, A. A., Hünenberger, P. H., Krüger, P., Mark, A. E., Scott, W. R. P., and Tironi, I. G. (1996).
267. Dominguez, C., Boelens, R., and Bonvin, A. M. (2003) J Am Chem Soc 125, 1731-7.
268. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr D Biol Crystallogr 54 ( Pt 5), 905-21.
269. Linge, J. P., O'Donoghue, S. I., and Nilges, M. (2001) Methods Enzymol 339, 71-90.
270. Güntert, P., Mumenthaler, C., and Wüthrich, K. (1997) J Mol Biol 273, 283-98.
271. Herrmann, T., Güntert, P., and Wüthrich, K. (2002) J Mol Biol 319, 209-27.
272. Hori, R., Pyo, S., and Carey, M. (1995) Proc Natl Acad Sci U S A 92, 6047-51.
273. Roberts, S. G., Ha, I., Maldonado, E., Reinberg, D., and Green, M. R. (1993) Nature 363, 741-4.
274. Gupta, R., Emili, A., Pan, G., Xiao, H., Shales, M., Greenblatt, J., and Ingles, C. J. (1996) Nucleic Acids Res 24, 2324-30.
275. Chou, S., and Struhl, K. (1997) Mol Cell Biol 17, 6794-802.
276. Cousens, D. J., Greaves, R., Goding, C. R., and O'Hare, P. (1989) Embo J 8, 2337-42.
277. Frankel, A. D., and Kim, P. S. (1991) Cell 65, 717-9.
278. Freedman, S. J., Sun, Z. Y., Poy, F., Kung, A. L., Livingston, D. M., Wagner, G., and Eck, M. J. (2002) Proc Natl Acad Sci U S A 99, 5367-72.
279. Dames, S. A., Martinez-Yamout, M., De Guzman, R. N., Dyson, H. J., and Wright, P. E. (2002) Proc Natl Acad Sci U S A 99, 5271-6.
280. Lo Conte, L., Chothia, C., and Janin, J. (1999) J Mol Biol 285, 2177-98.
281. Roberts, S. G., and Green, M. R. (1994) Nature 371, 717-20.
282. Hall, D. B., and Struhl, K. (2002) J Biol Chem 277, 46043-50.
283. Kobor, M. S., Simon, L. D., Omichinski, J., Zhong, G., Archambault, J., and Greenblatt, J. (2000) Mol Cell Biol 20, 7438-49.



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