The surname MOIZUK is very likely an Americanized version of a variant spelling of MOJZUK. This name comes from the name Mojzesz, "Moses," and is an Eastern-Polish form meaning basically "son of Moses."
This might suggest Jewish ancestry, but doesn't have to; in medieval times the name Moses was used by both Christians and Jews and it wasn't until later that the name came to be associated exclusively with Jews.
Alternate spellings of the name include Moiziuk, Mojzuik, Moisic and Moizuik.
As of 1990 there were 105 people in Poland named MOJZUK, living in the following Provinces: Warsaw (9), Bialystok (24), Lomza (4), Olsztyn (7), Sieradz (4), Suwalki (46), Szczecin (3), Walbrzych (1), Wroclaw (5), Zielona Gora (1).
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William F. "Fred" Hoffman
Author, Polish Surnames: Origins & Meanings
Publications Editor, Polish Genealogical Society of America
www.pgsa.org