Publication List

1. Mark L Nelson, Roger Frechette, Upul Bandarage et al. “7-Substituted tetracycline compounds”, PCT WO 0204407, 2002.

2 Ramani R. Bandarage, Upul K. Bandarage, Xinqin Fang, David Garvey, Joesph Schroeder, S. William Tam "Nitrosated and nitosylated cyclooxygenase-2 inhibitors, compositions and methods of use",WO 00145703, 2001.

3. Upul K. Bandarage, Qing Dong, Xinqin Fang, David Garvey, Joesph Schroeder, Tiansheng Wang “Compounds, compositions and methods to prevent toxicity induced by nonsteroidal anti inflammatory drugs”, U.S. Patent 6,297,260 B1, 2001.

4. Upul K. Bandarage*, Martin E. Kuehne, Stanley D. Glick "Chemical synthesis and biological ealuation of 18-methoxycoronaridine(18-MC) as a potential anti-addictive agent", Current Med. Chem. - Central nerveous system agents, 2001, 1, 113-123.

5. Upul. K. Bandarage*, David R. Janero "Nitric oxide-releasing nonsteroidal anti-inflammatory drugs: novel gastrointestinal-sparing drugs" Mini-Rev. in Med. Chem.,2001,1 , 57-70.

6. Martin Kuehne, Timothy Wilson, Upul K. Bandarage "Enantioselective syntheses of coronaridine and 18-methoxy coronaridine", Tetrahedron 2001,57 ,2085-2094.

7. Xinqin Fang, Upul K. Bandarage, Tiansheng Wang, Joseph D. Scheroeder, David S. Garvey, Joseph D. Scheroeder," First examples of oxidizing secondory alchol to ketones in the presence of disulfide functional group: Synthesis of novel diketone disulfide", J.Org. Chem, ,2001 ,66 , 4019-4021.

8. Upul. K. Bandarage*, Joy Saha, Greg Mercer, Frank Fang, David R. Janero, David S. Garvey, Joseph D. Scheroeder, Gorden Letts, S. Willam Tam “Nitrosothiol esters of diclofenac: synthesis and pharmacological characterization as gastrointestinal-sparing prodrugs”, J.Med. Chem, 2000 , 43 , 4005-4016.

9. Upul K. Bandarage, Martin E. Kuehne, Stanley D. Glick "Total syntheses of racemic albifloranine and its anti-addictive congeners, including 18-methoxycoronaridine", Tetrahedron, 1999 , 55 , 9405-9424.

10 S.D. Glick, I.M. Maisonneuve, L.B Hough, M.E.Kuehne, U.K Bandarage"18_methoxycoronaridine: A novel iboga alkaloids congener having potential anti-addictive efficacy" CNS Drug Reviews, 1999 , 5, 27-42.

11. B.J. Vilner, W. Williams, U.K. Bandarage, M.E. Kuehne, C.M. Bertha, W.D. Bowen " Neurotoxic effect of iboga alkaloids may be meditated by sigma-2 receptors. in: Problem of drug dependence, 1997: Preceedings of the 59th annual scientific meeting, Natinal Institute on drug abuse research monograph 178. (L.S. harris, ed), U.S. Government Printing Office, Wasington DC, 1998 , p 235.

12. W. Williams, U.K. Bandarage, M.E. Kuehne, C.M. Bertha, W.D. Bowen " Structure activity studies for binding of iboga alkaloids to sigma receptors. in: Problem of drug dependence, 1997: Preceedings of the 59th annual scientific meeting, Natinal Institute on drug abuse research monograph 178. (L.S. harris, ed), U.S. Government Printing Office, Wasington DC, 1998 , p 236.

13.Martin E. Kuehne, Upul K.Bandarage, A. H. Hammach, Y. Li, T. Wang "Application of ferrocenylalkyl auxiliaries to synthesis of Indolene alkaloids:Enantioselective syntheses of Vincadifformine, pseudo and 20-epipseudovincadifformine, Tabersonine, Ibophyllidine and Mosaambine" J. Org. Chem., 1998 , 63, 2172-2183.

14. S.D. Glick, I.M. Maisonneuve, K. E. Viskar, K.A. Fritz, U.K. Bandarage, M.E. Kuehne, " 18-Methoxycoronaridine attenuates nicotine-induced dopamine release and nicotine preferences in rats"Psycopharmacology, 1998 , 139 , 274-280.

15. A. H. Rezvani, D.H. Overstreet, Y. yang, I.M. Maisonneuve, U.K. Bandarage, M.E. Kuehne, S.D. Glick " Novel nontoxic ibogaine analogue (18-Methoxycoronaradine) in alcohol - alcohol prefering rats,, Pharmacology, Biochemistry and Behavior, 1997 , 58, 615-619.

16. W.D,. Bowen, B.J. Vilner, W. Williams, U.K. Bandarage, M.E. Kuehne" Novel ibogaine analogs as selective sigma 2 receptor probes: Ligand binding and functional assys Society for Neuroscience Abstracts 23, 1997 , 2319, #905.7.

17. I.M. Maisonneuve, K. E. Viskar, G. L. Mann, U.K. Bandarage, M.E. Kuehne, S.D. Glick " Time-dependent interactions between iboga agents and cocaine"European Journal of pharmacology, 1997 336 123-126.

18. Neelakanthi E.Gunawardena, Upul K. Bandarage, "4-Methyl-5-nonanol (Ferruginol) as an aggregation pheromone of the coconut pest, Rhynchophorous Ferrugineus F.(coleptera:curculionidae): synthesis and use in a preliminary field assay", Journal of Science Council of Sri Lanka, 1995, 23 (2), 71-79. Chem.Abst. 1996, 124, 138632t.

19. Martin E. Kuehne, Upul K. Bandarage "An alternative enantioselective generation of intermediate in the total synthesis of vinblastine: Enantioselection in secodine-type reaction induced by alpha-ferrocenyl ethyl N-substituents", J. Org. Chem., 1996 , 61, 1175-1179.

20. S.D. Glick, M.E. Kuehne, I.M. Maisonneuve, U.K. Bandarage and H.H. Molinari "18-Methoxycoronaradine, a Non-toxic Iboga Alkaloid Congener: Effects on Morphine and Cocaine Self-administration and on Mesolimbic Dopamine Release in Rats", Brain Research, 1996, 719, 29 - 35.

21. R. T. layer, P. Skolnick, C. M. Bertha. M. E. Kuehne. U. K. Bandarage " Structurally Modified Ibogaine analogs exibit diffring affinities for NMDA receptors" Eur. J. Pharmacol., 1996 309, 159-165

22.Upul K. Bandarage, Lyall R. Hanton, Robin A.J. Smith "Synthesis and Structural Characterization of Dithiacyclophanes Derived From Biaryldithiols", Tetrahedron, 1995, 51, 787-800.

23. Upul K. Bandarage, Gavin F. Painter, Robin A.J. Smith "Resolution of (1,1'-Binapthalene)-2,2'-dithiol via Diastereoisomeric Dithioacetals Derived from D -Glucose", Tetrahedron: Asymmetry, 1995, 6, 295-300.

24.Upul K. Bandarage, Jim Simpson, Robin A. J. Smith, Rex T.Weavers.; "Conformational Polymorphism and Thermo-rearrangement of 2,2'-Bis-O-(N,N-dimethylthiocarbamato)-1,1'-binaphthalene-2,2'-dithiol,Tetrahedron, 1994 , 50, 3463-3472.

Presentations

1. Upul K. Bandarage*, Liqing Chen, Xinqin Fang, David S. Garvey, Alicia Glavin, David R. Janero, L. Gordon Letts, Gregory J. Mercer, Joy K. Saha, Joseph D.Schroeder, Matthew J. Shumway, S. William Tam., "Synthesis and biological evaluation of nitrosothiol esters of diclofenac as a new class of gastrointestinal-sparing prodrugs", 220th ACS National meeting (Med. Chem.), WDC, August 20-24, 2000.

2. U.K. Bandarage, Q. Dong, L. Chen, X. Fang, D. S. Garvey, D. R. Janero, L. G. Letts, G. J. Mercer, Joy K. Saha, J D.Schroeder, M. J. Shumway, S. W. Tam., "Synthesis and pharmacological evaluation of gastrointestinal-sparing nitrosothiol esters of nonsteroidal anti-inflammatory drugs", First international conference: Biology, chemistry and therapeutic applications of nitric oxide, San Francisco, CA, June 3-7, 2000.

3. Joy K. Saha, Upul K. Bandarage, Linquing Chen, Alicia Galvin, David R. Janero, David S. Garvey, Joseph D. Scheroeder, Gorden Letts, S. Willam Tam. "NMI-377: A novel nitrosothiol-diclofenac derivative with gastrointestinal-sparing anti-inflammatory and analgesic activities" American gastroenterological association (Digestive disease week), May 2000.

4. Upul K. Bandarage*, Joy K. Saha, Joseph D.Schroeder, David S. Garvey, Greg J. Mercer, Liqing Chen, Alicia Glavin, David R. Janero, L. Gordon Letts, Joseph D.Schroeder, S. William Tam., "NMI-377, A nitric oxide donating diclofenac derivative with gastroprotective properties", 218th ACS National meeting (Med. Chem.), New Orleans, August 22-26, 1999.

5. S.M. Tam, J.K. Saha, D.S. Garvey, J.D. Schroeder, U. Bandarage, Q. Dong, D.R. Janero, L. Chen, T.E. Shelekhin, A. Glavin, L.G. Letts, "Nitric oxide donating NSAIDs", International conference on inflammopharmacology and sixth symposium on side-effects of anti-inflammatory drugs, Chateau Elan, Braslton, Georgia, May 23-26, 1999.

6. Joy K. Saha, Upul K. Bandarage, David R. Janero, Linquing Chen, Alicia Galvin, David S. Garvey, Joseph D. Scheroeder, Gorden Letts, S. Willam Tam."Nitric oxide releasing diclofenac derivative NMI-346 is a novel gastrointestinal sparing NSAID", American gastroenterological association (Digestive disease week), May 1999.

7. Joy K. Saha, Upul K. Bandarage, David R. Janero, Linquing Chen, David S. Garvey, Joseph D. Scheroeder, James F. Ewing, Gorden Letts, S. Willam Tam. "NMI 346, A novel nitrosothiol diclofenac derivative as gastroprotective anti-inflammatory and analgesic drug" poster presented at 9th international conference inflammation research association. Hershey, PA, Novemebr 5, 1998.

8. Upul K. Bandarage, Hakim Hammach, Matin E. Kuehne "Enantioselective syntheses of aspidosperma alkaloids", poster presented at 14th annual Esther and Bingham J.Humphrey Memorial symposium, University of Vermont, October 07,1995.

9. Upul K. Bandarage, Martin E. Kuehne "Enantioselective Syntheses of Iboga Alkaloids through the Use of chiral ferrocenyl auxiliaries in intramolecular Diels Alder reaction", presented at 24th ACS Northwest Regional Meeting, Sheraton Hotel, Burlington ,Vermont, June 19-23, 1994.

10. Upul K. Bandarage, Robin A. J. Smith "Dithioacetalization: Application to optical resolution of 1,1'- binaphthalene-2,2'-dithiol", presented at 12th annual Esther and Bingham J. Humphrey Memorial symposium, University of Vermont, October 09,1993.

11 Upul K. Bandarage , Robin A. J. Smith "Syntheses and reactions of chiral carbocations", poster presented at 60th Anniversary conference, University of Canterbury, Christchurch, New Zealand, August 26, 1991.

12. Upul K. Bandarage, Neelakanthi E. Gunawardena "Preliminary Study on the Pheromones of Hyblaea puaera and Hapalia macharalis: The two major pests on teak (tectana grandis)", Proceedings, Sri Lanka Association for Advancement of Science 42 (1), DT5, 1986, University of Colombo, Sri Lanka.

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