Medical Evidence Showing Circumcised Males Are Less Susceptible To Urinary Tract Infections


Infant Bladder Infection Common

Reuters Health, New York, May 19, 1997. Dr.Thomas Newmon, Professor of Pediatrics, University of California San Francisco (UCSF)


"More than 1 in 10 babies with fever going to the pediatrician may be suffering from--often undiagnosed--urinary tract infections(UTIs) experts say.
"We know that fever in this age group can be due to life threatening illness, but most of these babies have colds or other mild illnesses that get better themselves, said Dr. Thomas Newman, an associate professor of pediatrics at the University of California San Francisco (USCF). He believes "the difficult issue is how to identify the few babies needing treatment without doing lots of unecessary test on all remaining infants."

Newman and his USCF colleagues suspected that UTIs might be more prevalent among infants 3 months of age than generally thought.

They canvassed over 200 pediatricians involved in the Pediatric Research in Office Settings (PROS) Network, affiliated with the American academy of Pediatrics
The researchers perused the records of nearly 900 babies who were brought to PROS clinics after experiencing unexplained fever. Less than half of those infants were asked to give urine to be tested for bacterial infection.
But of those 420 infants who were evaluated via urine sample, 50 (11%) tested positive for bladder infection.

Seven of those 50 infants had concurrent bacterial infection (septicemia), which can be dangerous- and in some cases, even fatal. Many bacterial blood infections might not initially present with severe symptoms, however-in fact, only four of the seven babies appeared to be more than "slightly ill", according to the UCSF report. And none of those (clinically) ill infants displayed feverish symptoms while in the pediatrician's office, though their temperatures did rise when home.

"Evaluation of fever in infants less than 3 months old is a major challenge," Newman admits.

He believes that, since UTI symptoms can be either subtle or nonexistent, a routine urine test becomes imperative in infants presenting with fever.

In a related finding, researchers discovered that the strongest risk factor for infant UTI was being an uncircumcised male. Those babies were found to have 10 times the infection rate of their circumcised counterparts.

Newman presented his findings at the recent annual meetings of the Pediatric Academic Societies in Washington, D.C."


Corroborative Evidence For the Decreased Incidence Of Urinary Tract Infections In Circumcised Male Infants

Wiswell TE, Roscelli JD. Pediatrics 1986; 78:96-99

In a worldwide study of all male infants born in U.S. Army hospitals over a ten year period"..noncircumcised male infants had tenfold greater incidence of infection than circumcised male infants."As the number of circumcisions decreased over the ten year period from 85% to 74%, there was a concommitant increase in the overall number of urinary tract infections in males"


Links To Medical Articles

Does Circumcision Alter The Periurethral Bacterial Flora?

Pediatr Surg Int 1998 Mar;13(2-3):146-148> Wijesinha SS, Atkins BL, Dudley NE, Tam PK Department of Pediatric Surgery, John Radcliffe Hospital, Oxford, UK..

Comparative Periurethral Bacteriology Of Uncircumcised And Circumcised Males.

Genitourin Med 1997 Aug;73(4):288-290 Serour F, Samra Z, Kushel Z, Gorenstein A, Dan M Paediatric Surgery Unit. E Wolfson Hospital, Holon, Israel.


Effect Of Circumcision On Incidence Of Urinary Tract Infection In Preschool Boys.

J Pediatr 1996 Jan;128(1):23-27 Craig JC, Knight JF, Sureshkumar P, Mantz E, Roy LP Department of Nephrology, Royal Alexandra Hospital for Children, Sydney, Australia.


Lack Of Circumcision Increases The Risk Of Urinary Tract Infection In Young Men..

JAMA 1992 Feb 5;267(5):679-81Spach DH; Stapleton AE; Stamm WE (92114226NLM).


Urinary Tract Infections In Healthy University Men.

J Urol 1993 May;149(5):1046-1048 Krieger JN, Ross SO, Simonsen JM Department of Urology, University of Washington, Seattle.

Urinary Tract Infections And The Uncircumcised State: An Update.

Clin Pediatr (Phila) 1993 Mar;32(3):130-134 Wiswell TE, Hachey WE Department of Pediatrics, Walter Reed Army Medical Center, Washington, DC 20307-5001.

Phimosis As A Pathogenetic Factor In Urinary Tract Infection And Vesicoureteral Reflux.

Nippon Hinyokika Gakkai Zasshi 1994 Jun;85(6):953-957 Matsuoka H, Kajiwara I, Tahara H, Oshima K Department of Urology, School of Medicine, Fukuoka University, Japan.

Pyelonephritis In Male Infants: How Important Is The Foreskin?

J Urol 1992 Aug;148(2 Pt 2):733-736 Rushton HG, Majd M Department of Urology, Children's National Medical Center, Washington, D.C. 20010.

Urinary Tract Infection and Circumcision. A Case -Control Study.

Am J Dis Child 1989 Mar;143(3):348-50. Herzog LW


Effect Of Circumcision Status On Periurethral Bacterial Flora During The First Year Of Life.

J Pediatr 1988 Sep;113(3):442-6 Wiswell TE; Miller GM; Gelston HM Jr; Jones SK;Clemmings AF


Adherence Of Bacteria To Human Foreskins.


J Urol 1988 Nov;140(5):997-1001
Fussell EN, Kaack MB, Cherry R, Roberts JA Department of Urology, Tulane University School of Medicine, Delta Regional Primate Research Center, Covington, Louisiana.


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