Lyme Disease Hall of Shame
Pierce Gardner, MD
Lyme disease is a serious bacterial infection caused by a tick bite and
affects humans and animals.
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This page contains citations and abstracts for medical and scientific articles from the National Institutes of Health (NIH), National Library of Medicine (NLM) MEDLINE database about Lyme disease by Pierce Gardner, MD.
Table of Contents
General information about Pierce Gardner, MD
MEDLINE search link for Lyme disease citations and abstracts with Gardner P as author
Summaries of all MEDLINE citations on Lyme disease for Pierce Gardner, MD
Complete text of all MEDLINE citations on Lyme disease for Pierce Gardner, MD
Back to the Lyme Disease Hall of Shame home page
For more information on Lyme disease
General information about Pierce Gardner, MD
Pierce Gardner, MD
------------------------------------
mailto:pgardner@dean.som.sunysb.edu
University Hospital, Medical Center, SUNY Stony Brook
Medicine Administration Department
L4-157 Health Sciences Center
Stony Brook, NY 11794-8432
Phone 631-444-1030
The following link was used to find all MEDLINE citations and abstracts pertaining
to Lyme disease with Gardner P as one of the authors:
MEDLINE - Gardner P AND Lyme disease - 5 citations found on 9 Feb 00
Summaries of all MEDLINE citations on Lyme disease for Pierce Gardner, MD
1 - Long-term outcomes and management of patients with Lyme disease
[editorial] [No abstract available.]
2 - Lyme disease vaccines [editorial] [No abstract available.]
3 - Empiric antibiotic treatment of patients who are seropositive for Lyme
disease but lack classic features. [No abstract available.]
4 - "For most patients with a positive Lyme antibody titer
whose only symptoms are nonspecific myalgia or fatigue the risks and
costs of empirical parenteral antibiotic therapy exceed the benefits.
Only when the value of patient anxiety about leaving a positive test
untreated exceeds the cost of such therapy is the empirical treatment
cost-effective."
5 - "The rapid rate of increase in reported cases of Lyme disease exceeds
that of any zoonotic disease, and the annual occurrence of cases is
greater than the sum of all other tick-borne illnesses in the United
States. This, in addition to the geographic spread of cases to most
of the United States, has greatly heightened investigative interests
in all aspects of Lyme disease and its control."
Complete text of all MEDLINE citations on Lyme disease for Pierce Gardner, MD
1
TITLE:
Long-term outcomes and management of patients with Lyme disease
[editorial]
See complete text at:
http://jama.ama-assn.org/issues/v283n5/full/jed90106.html
AUTHORS: Gardner P
NLM PUBMED CIT. ID: 10665707 NLM CIT. ID: 20127473
SOURCE: JAMA 2000 Feb 2;283(5):658-9
[No abstract available.]
2
TITLE:
Lyme disease vaccines [editorial]
AUTHORS: Gardner P
NLM PUBMED CIT. ID: 9758582 NLM CIT. ID: 98420304
SOURCE: Ann Intern Med 1998 Oct 1;129(7):583-5
[No abstract available.]
3
TITLE:
Empiric antibiotic treatment of patients who are seropositive for Lyme
disease but lack classic features. American College of Rheumatology and
the Infectious Diseases Society of America.
AUTHORS: Luft BJ; Gardner P; Lightfoot RW Jr
AUTHOR AFFILIATION:
Division of Infectious Diseases and School of Medicine, SUNY at Stony
Brook.
NLM PUBMED CIT. ID: 8054419 NLM CIT. ID: 94331489
SOURCE: Clin Infect Dis 1994 Jan;18(1):112
[No abstract available.]
4
TITLE:
Empiric parenteral antibiotic treatment of patients with fibromyalgia
and fatigue and a positive serologic result for Lyme disease. A cost-
effectiveness analysis [see comments]
AUTHORS: Lightfoot RW Jr; Luft BJ; Rahn DW; Steere AC; Sigal LH;
Zoschke DC; Gardner P; Britton MC; Kaufman RL
AUTHOR AFFILIATION:
Division of Rheumatology, Kentucky Clinic J515, University of Kentucky
Medical Center, Lexington 40536-0284.
COMMENTS:
Comment in: Ann Intern Med 1993 Sep 15;119(6):518
Comment in: Ann Intern Med 1993 Sep 15;119(6):528-9
NLM PUBMED CIT. ID: 8357117 NLM CIT. ID: 93362816
SOURCE: Ann Intern Med 1993 Sep 15;119(6):503-9
ABSTRACT:
PURPOSE: To examine the cost-effectiveness of empirical, parenteral
antibiotic treatment of patients with chronic fatigue and myalgia and
a positive serologic result for Lyme disease who lack classic
manifestations. DATA SOURCES: Peer-reviewed journals, opinion of
experts in the field, and published epidemiologic reports. STUDY
SELECTION: Consensus by authors on articles that indicated methods
for patient selection; on criteria used for diagnosis; on immunologic
methods used for classifying patients; on the dose and duration of
therapy; and on criteria by which responses to therapy were
ascertained. DATA EXTRACTION: In a cost-effectiveness model, the
costs and benefits of empirical parenteral therapy for patients
seropositive for Lyme disease were compared with a strategy in which
only patients having classical symptoms of Lyme disease were treated.
DATA SYNTHESIS: In areas endemic for Lyme disease, the incidence of
false-positive serologic results in patients with nonspecific myalgia
or fatigue exceeds by four to one the incidence of true-positive
results in patients with nonclassical infections. Treatment of the
former group of patients costs $86,221 for each true-positive patient
treated. The empirical strategy causes 29 cases of drug toxicity for
every case in the more conservative strategy. If patients were
willing to pay $3485 to eliminate anxiety about not treating possible
true Lyme disease, the empirical strategy would break even.
CONCLUSION: For most patients with a positive Lyme antibody titer
whose only symptoms are nonspecific myalgia or fatigue the risks and
costs of empirical parenteral antibiotic therapy exceed the benefits.
Only when the value of patient anxiety about leaving a positive test
untreated exceeds the cost of such therapy is the empirical treatment
cost-effective.
5
TITLE:
Lyme disease [published erratum appears in Infect Dis Clin North Am
1991 Sep;5(3):following xi]
AUTHORS: Buchstein SR; Gardner P
AUTHOR AFFILIATION:
State University of New York, Stony Brook.
NLM PUBMED CIT. ID: 2051010 NLM CIT. ID: 91268503
SOURCE: Infect Dis Clin North Am 1991 Mar;5(1):103-16
ABSTRACT:
The rapid rate of increase in reported cases of Lyme disease exceeds
that of any zoonotic disease, and the annual occurrence of cases is
greater than the sum of all other tick-borne illnesses in the United
States. This, in addition to the geographic spread of cases to most
of the United States, has greatly heightened investigative interests
in all aspects of Lyme disease and its control.
For more information on Lyme disease see:
Lots Of Links On Lyme Disease
Comments or questions concerning this page should be directed to
Art Doherty.
Last updated on 9 February 2000 by
Art Doherty
Lompoc, California
doherty@utech.net
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