Early Ovarian Cancers Detected at Stage IA by TVS Screening
.Transvaginal sonography (TVS) detects structures using ultrasound. It is much better suited for detecting structures within the abdominal cavity than abdominal ultrasound.
TVS images can be accessed from the table below.
The intent of ovarian screening is to detect ovarian cancers at the earliest possible stage when they are most likely to be cured. This table summarizes the screening program's experience with Stage IA ovarian cancers.
(Cases underlined in blue can be clicked on for the sonographic images).
|
Case |
A |
B |
F |
G |
||||
|
Age at Dx |
72 |
50 |
42 |
36 |
55 |
66 |
64 |
63 |
|
CA-125, U/ml |
7 |
14 |
14 |
|
|
37 |
|
|
|
Physical Exam |
Normal |
Normal |
Palpable |
Normal |
Normal |
Normal |
Normal |
Normal |
|
TVS size, cm3 |
75 |
19.4 |
14.7 |
32.1 |
14.7 |
39.8 |
25 |
223.1 |
|
TVS – cystic |
+ |
+ |
|
+ |
+ |
|
+ |
+ |
|
TVS – solid |
|
+ |
|
|
|
|
|
|
|
TVS – papillation |
+ |
|
|
|
|
|
|
|
|
TVS – septation |
|
|
|
+ |
+ |
|
+ |
+ |
|
TVS – MI |
5 |
8 |
1 |
5 |
6 |
6 |
3 |
8 |
|
Tumor Stage |
IA |
IA |
IA |
IA |
IA |
IA |
IA |
IA |
|
Treatment |
S |
S & C |
S |
S |
S |
S |
S & C |
S |
|
Status |
A & W |
A & W |
A & W |
A & W |
A & W |
A & W |
A & W |
A & W |
|
DX Date |
Jan-90 |
Aug-90 |
Mar-93 |
Mar-93 |
May-94 |
Jan-95 |
April-96 |
Jul-97 |
|
Years Post Dx |
9.5 |
9.0 |
6.0 |
6.0 |
5.2 |
4.5 |
3.2 |
2.0 |
S = surgery
S & C = surgery + chemotherapy
A & W = alive and well
Dx = diagnosis
|
Case |
Histology |
|
A |
Granulosa cell tumor, Grade 2 |
|
B |
Adenocarcinoma, Grade 3 |
|
C |
Serous cystadenocarcinoma, Grade 3 |
|
D |
Endometriod carcinoma , Grade 1 |
|
E |
Granulosa cell tumor,Grade 2 |
|
F |
Endometriod carcinoma, Grade 2 |
|
G |
Endometriod carcinoma |
|
H |
Borderline serous ovarian epithithelial Tumor |