Makale1 Başlık     : Flexible bronchoscopy in the management of congenital lobar emphysema in the    neonate.
Yazarlar : Phillipos EZ, Libsekal K
Adres     : Children's Health Centre, University of Alberta Hospital, Edmonton, Canada. ephillip@gpu.srv.ualberta.ca
Kaynak   : Can Respir J 1998 May-Jun;5(3):219-21

Özet    :  This paper describes the case of a 3 kg neonate who had congenital lobar emphysema of the left upper lobe (LUL). He was in severe respiratory distress with a fraction of inspired oxygen of 0.8. Chest x-ray showed hyperlucent expanded left hemithorax and marked mediastinal shift. Following flexible bronchoscopy and introduction of ultrathin bronchoscope into the LUL bronchus, symptoms and chest x-ray improved markedly. Flexible bronchoscopy resulted in emergency relief of his initial respiratory distress, and left upper lobe lobectomy was performed electively three days later.

Makale 2 Başlık     : [Polyalveolosis: pathogenesis of congenital lobar emphysema]? [Article in Portugese]
Yazarlar : Giudici R, Leao LE, Moura LA, Wey SB, Ferreira RG, Crotti PL
Adres     : Departamentos de Cirurgia, Medicina e Anatomia Patologica, Universidade Federal de Sao Paulo.
Kaynak : Rev Assoc Med Bras 1998 Apr-Jun;44(2):99-105

Özet       : Congenital lobar emphysema is an unusual condition and its pathogenesis remains unknown. The variety of findings in pathology studies of the resected specimens led to increasing academic interest. About 50 per cent of the cases have no definitive diagnosis in pathology. The most recent theory proposes an increased number of alveoli within each acinus (polyalveolar lobe). PURPOSE: The aim of this paper is to report the morphometric measures of surgical specimens of 12 patients with congenital lobar emphysema, using the Emery and Mithal technique (radial alveolar count). METHODS: We made a case-control study, classifying the cases by age. Mann-Whitney's U test and linear regression techniques were used in data analysis: Mann-Whitney's U in comparing the cases and respective controls and linear regression to evaluate the influence of age in the measures found. RESULTS: The results revealed a significantly higher radial alveolar count than expected for the age group under 3 years; no difference was observed in the age group between 3 and 7 years and in children older than 7, the radial alveolar count was lower than expected. The normal development of the lung consists in an increasing number of alveoli increase from birth until adulthood, but this number remains constant, independent of age in congenital lobar emphysema. CONCLUSIONS: Such findings allow us to conclude that polyalveolar lobe can and must be diagnosed by a simple and practical method, such as the radial alveolar count, which decreases the incidence of the unknown etiology. The findings of an increased number of alveoli on patients younger than 3 is related to congenital lobar emphysema, since the number of alveoli does not increase in congenital lobar emphysema, just the opposite to what one would expect in the normal development of the lung.
  

Makale 3 Başlık     : Congenital lobar emphysema in congenital cytomegalovirus infection.
Yazarlar : Carrol ED, Campbell ME, Shaw BNJ, Pilling DW
Adres     : Regional Neonatal Intensive Care Unit, Liverpool Women's Hospital, Crown Street, Liverpool L8 7SS, UK.
Kaynak  : Pediatr Radiol 1996 Dec;26(12):900-2
Özet       : We report a case of congenital lobar emphysema diagnosed antenatally in an infant of 32 weeks' gestation. Histology and serology confirmed infection with cytomegalovirus (CMV). CMV pneumonitis leading to inflammation and obstruction in the bronchial tree may have resulted in the development of congenital lobar emphysema.

Makale 4 Başlık     : Bronchoscopic appearances of congenital lobar emphysema.
Yazarlar : Doull IJ, Connett GJ, Warner JO
Adres     : Department of Child Health, University of Southampton, Southampton General Hospital, UK.
Kaynak  : Pediatr Pulmonol 1996 Mar;21(3):195-7
Özet       : Although decreased bronchial cartilage is found in 50% of cases of congenital lobar emphysema (CLE), it can only be surmised that this defect produces a ball valve effect with consequent overinflation. We describe the flexible bronchoscopic features of CLE in a 3-year-old child. The observed airway patency during inspiration, and dynamic airway collapse on expiration suggests that bronchomalacia contributes to lung overinflation in these cases.

Makale 5 Başlık     : [Congenital lobar emphysema in childhood]. [Article in Bulgarian]
Yazarlar : Mikhailova V
Kaynak  : Khirurgiia (Sofiia) 1996;49(3):8-12
Özet       :  Over a 20-year period, thirty-two children with infantile (congenital) lobar emphysema (ILE) are subjected to treatment in the department of pediatric chest surgery--Emergency Medicine Institute "N. I. Pirogov". The age distribution of the patients is as follows: neonates--7 (21.8 per cent), sucklings--17 (53.8 per cent), 1 y.--5 (15.6 per cent), 2 y.--2 (6.2 per cent), 12 y.--1 (3.1 per cent). In seventeen children (53.3 per cent) the lobar emphysema is located in the left upper lobe. The onset of the clinical picture is in the neonatal period (17 cases, 53.3 per cent) and in the suckling age (13 cases, 40.6 per cent), and becomes manifest with: dyspnea--16 children (50.0 per cent), tachypnea--26 (81.2 per cent) and cyanosis--18 (56.2 per cent). Twenty-seven children are admitted with varying degree respiratory insufficiency (84.4 per cent). Diagnosis is made on the ground of conventional roentgen examinations mainly. Stenosis of the respective lobar bronchus is discovered in 8 children by CAT and bronchoscopy. Scarce vascular pattern is established angiopulmographically in 87.5 per cent of children, and fan-like displacement of the vessels-in 75.0 per cent. All children undergo operation--removal of the emphysematous lobe. Morphological study of the resected lung shows cartilage deficit in the bronchial wall in 14 children (34.5 per cent), bronchial stenosis in 26.2 per cent whereas in 43.8 per cent the underlying cause of ILE is unclear. In 4 children (12.5 per cent) the outcome is lethal because of inflammatory pulmonary process in the postoperative period.
  

Makale 6 Başlık     : Congenital lobar emphysema. A case report.
Yazarlar : Kaklikkaya I, Zengin M, Ozdemir R, Yavas D, Ozcan F
Adres     : Department of Thoracic and Cardiovascular Surgery, Black Sea Technical University, Medi cal Faculty, Trabzon, Turkey.
Kaynak  : J Cardiovasc Surg (Torino) 1994 Aug;35(4):359-61
Özet       :  One infant, age 19 days, with congenital lobar emphysema whose main symptoms included dyspnea, cyanosis and severe infant Respiratory Distress Syndrome, was presented in this paper. The most reliable diagnostic tool was chest x-ray films with anteroposterior and lateral views. As additional diagnostic method, thorax computerized tomography was also used. The affected lobe was the left upper lobe. Resection of the affected lobe was performed with good results.

Makale 7 Başlık     : Deficiency of cartilage in the segmental bronchi of a child: congenital or acquired?
Yazarlar : Elfeldt RJ, Schmidt D, Thies J, Schroder DW, Seiffert P
Adres     : Department of General and Thoracic Surgery, University of Kiel, Germany.
Kaynak  : Ann Thorac Surg 1994 Aug;58(2):565-7
Özet       : The case of a 4-year-old girl suffering from a severe bronchopneumonia of the left lower lobe is presented. Microscopically no cartilage was found in the resected lobe distal to the lobar bronchus. The case is unusual because a congenital lobar emphysema associated with an aplasia of bronchial cartilage has to be considered as well as secondary cartilage destruction due to chronic relapsing inflammations.
 
 
    ana sayfaya dön       eski konulara dön