June 6, 2001
     General Cancer

 

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US Cancer rates decline, breast cancer up

WASHINGTON ­ June 6, 2001 (Cancer Digest) -- Fewer people in the United States get cancer and the number of people dying from the disease is declining, according to new data released by a consortium of cancer registries.

That good news was tempered by an increase in the number of people diagnosed with breast cancer between 1992 and 1998, the period covered by the report compiled by the North American Association of Central Cancer Registries.

The report, released by Health and Human Services Secretary Tommy G. Thompson, summarizes the progress of the nation's efforts to cure cancer.

"This welcome news on declining rates underscores the incredible progress we've made against cancer, but it also reminds us that our fight is far from over," said Thompson in a press release.

"That is why we are aggressively promoting cancer-related research at the National Institutes of Health (NIH). HHS has proposed an increase of $514 million for cancer-related research at NIH in 2002, a 12 percent increase over current year spending," he said.

The report shows that the incidence rate for all cancers combined -- the number of new cancer cases per 100,000 persons per year -- declined on average 1.1 percent per year between 1992 and 1998.

This overall trend reversed a pattern of increasing incidence rates from 1973 to 1992. Most of the decline can be attributed to a 2.9 percent yearly decline in white males and a 3.1 percent yearly decline in black males.

"These findings highlight the progress we've made against cancer but also underscore the critical need for research and for equitably applying what we already know to sustain this progress," said NCI Director Dr. Richard D. Klausner.

Four cancer sites -- lung, prostate, breast, and colorectum -- accounted for about 56 percent of all new cancer cases and were also the leading causes of cancer deaths for every racial and ethnic group, which includes white, black, Asian/Pacific Islander, American Indian/Alaska Native, and Hispanic populations. Because these sites comprise over half of all cancer cases, they have a strong influence on overall cancer trends.

Breast cancer makes up 16.3 percent of all cancer cases and accounts for 7.8 percent of all deaths due to cancer. Breast cancer death rates have continued to decline due to improvements in early detection and treatment. However, breast cancer incidence rates have increased by more than 40 percent from 1973 to 1998.

Why breast cancer cases continue to rise is unknown, according to Dr. Brenda Edwards, final author of the report. One explanation is that more early stage disease is being diagnosed, suggesting that use of aggressive screening and early detection, primarily mammography, may account for part of this increase.

"The extent to which other factors, such as more obesity and post-menopausal hormone use, may contribute to the increase is unknown," said Edwards.

A similar rise in prostate cancer, which accounts for 14.8 percent of all cases, occurred in the late 1980s with the introduction of screening for Prostate Specific Antigen (PSA). Subsequently, however, rates have started to decline.

Lung cancer remains the biggest contributor to the nation's overall cancer rate accounting for 13.2 percent of the cases and 29 percent of cancer deaths. Overall, lung cancer incidence rates decreased 1.6 percent per year between 1992 and 1998, due mainly to a decline of 2.7 percent per year in men and a leveling off of rates in women, both manifestations of reductions in tobacco smoking since the 1960s.

Besides breast cancer, 10 other relatively rare cancers accounting for 13 percent of all cancers saw increased incidence during the reporting period.

The report is based on incidence data from NCI's Surveillance, Epidemiology, and End Results (SEER) program, the CDC's National Program of Cancer Registries (NPCR), and NAACCR. Mortality data come from the CDC's NCHS.

Additional information and background on this report can be found on the NCI's Questions and Answers Web page.   


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