May 29, 2001
     Prostate Cancer

 

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Company facing huge fines in prostate cancer drug case

BOSTON -- May 29, 2001 (Cancer Digest) -- The maker of a commonly prescribed prostate cancer medicine may be facing the largest fines ever levied for health fraud according to reports in Monday's Boston Globe and the Associated Press.

In a copyrighted story, the Globe disclosed that TAP Pharmaceuticals is negotiating with the U.S. Attorney's office to settle federal allegations that it used taxpayer's funds to bribe doctors to prescribe the drug Lupron Depot, a hormone blocking drug, and artificially inflated its price

TAP, which has not been charged with any crime, is nonetheless expected to pay the government what could be the largest fine ever in a federal health fraud case, topping the $840 million paid last year by the hospital company HCA.

At the same time patients who were prescribed the drug have filed a class action lawsuit against the company alleging the company's inflated prices resulted in millions of dollars of overcharges.

Court documents charge that the company bribed individual doctors with as much as $70,000 in free drug samples, for which the doctors then billed Medicare and the patients. The company also allegedly offered an unnamed health maintenance organization in Massachusetts $65,000 in an effort to get it to switch from using a competing drug.

In addition, the government accused TAP of controlling the average price used for government reimbursement to ensure doctors would make at least a $100 per dose.

The Globe quoted Jeffrey Kodroff, lead attorney for the class action suit filed this month in US District Court, Boston as saying, ''It's a ripoff of Medicare and the patients who paid their 20 percent co-payments.''

Kim Modory, a spokeswoman for the Illinois-based company, declined comment on the class action suit or the company's marketing practices, but confirmed TAP was negotiating a settlement with the US attorney's office.

''The discussions in the investigation are ongoing,'' she told the Globe reporter, ''TAP conducts its business ethically.''

The US attorney's office declined to comment.

The alleged scheme involved physicians from across the country, including a Connecticut doctor who allegedly used his patients as bargaining chips to get bigger kickbacks from TAP, switching them back and forth between Lupron and a less-expensive drug made by another company. The doctor, Joseph Spinella of Bristol, pleaded guilty in March to conspiring to receive kickbacks.

Lupron has been on the market since 1985, when it was approved by the Food and Drug Administration for prostate cancer as an alternative to removal of the testicles. The drug is injected by doctors into the arm muscle or buttocks once a month or once every three or four months, often for the remainder of the patient's life. In subsequent years, the drug was also approved for use against endometriosis, uterine fibroids, and early puberty.

Medicare, the federal health program that insures the elderly, paid billions of dollars over the past decade for Lupron. The drug is a hormone injection that blocks the body's production of testosterone and helps halt the progression of prostate cancer.

Some government investigators believe Medicare paid at least $100 million a year more than it should have from 1993 to 1998. Authorities are also investigating whether Medicaid, the state-federal health insurance program for the poor, overpaid as well.


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