Quickly determine which guest hates (or is allergic to) Cats the most. Sit on that lap. If you can arrange for particularly bad "tuna breath" (or extra dander), so much the better.
For sitting on laps or rubbing against trouser legs, select fabric which contrasts well with your fur. For example: white-furred Cats go to black wool clothing. NOTE: Velvet takes precedence over all other cloth.
For the guest who exclaims, "I love kitties!", be ready with aloof disdain, apply claws to stockings or arms, or use a quick nip on the ankle.
When walking among the dishes on the dinner table, be prepared to look surprised and hurt when scolded. The idea is to force your humans to reveal that they tolerate this behavior when company is not there.
Always accompany guests to the bathroom. It is not necessary to do anything -- just sit and stare. If you do feel active, try turning off the light switch if it is within reach; this is usually good for some laughs. Some Cats with a more prankish disposition like to hide behind the White Drinking Bowl and reach around to pat the human on the behind as s/he is sitting down just to watch him/her leap up in surprise. This will result in expulsion, but is worth it!