Name: Shulei Zhao
Title: Scientist
Lexicon Genetics, Inc.
4000 Research Forest Drive The Woodlands, TX 77381
Phone: 281-364-3269     Fax: 281-863-8088      Email: szhao@lexgen.com
Education
B.S. in Optical Engineering, Zhejiang University, 1983 M.S. in Optical Engineering, Zhejiang University, 1986
Ph.D. in Biomedical Engineering, Duke University, 1992
Postdoctoral Training
Yale University School of Medicine, 1992-1995
Baylor College of Medicine, 1995-2000
Research Experience
September 1983 - July 1986 (graduate student)
Department of Optical Engineering, Zhejiang University
Advisor: Prof. H-S. Long Optical information processing and holography, and computer-aided design of optical systems.
January 1987 - April 1992 (graduate student):
Department of Biomedical Engineering, Duke University;
Advisor: Dr. W. Monty Reichert
Development of a fiber optic biosensor system, characterization of protein-receptor interactions by fluorescence spectroscopy, protein binding kinetics and cooperativity and computer simulations.
May 1992- October 1995 (Postdoctoral Fellow)
Department of Ophthalmology and Visual Science,  Yale University School of Medicine
Advisor: Dr. Colin J. Barnstable
Development of mammalian retina using molecular biology and tissue culture techniques; roles of homeobox genes in cell fate determination of neural retina and retinal pigment epithelium; effects of growth factors on cell proliferation and differentiation.
November 1995 - July 2000 (Instructor) Department of Molecular and Cellular Biology, Baylor College of Medicine
Advisor: Dr. Paul A. Overbeek
Study of ocular genesis using transgenic mice; neural induction; roles of diffusible factors and transcription factors in retinal and RPE development and tissue type specification; cell cycle control in the developing retina;  transgenic mouse models for retinal angiogenesis and retinal degenerations.
	July 2000 - present (Scientist) Lexicon Genetics, Inc.
Technical Skills
Recombinant DNA techniques; various assays for DNA, RNA and proteins; polymerase chain reaction (PCR); construction and screening of genomic and cDNA libraries; cell and organ culture; tissue processing, histology and immunohistochemistry; microscopy and digital image processing; in situ hybridization with radioisotope and non-radioisotope-labeled RNA probes; extensive experience with rats and mice; preparation of DNA constructs and pronucleus microinjection for generating transgenic mice; manipulations of early-stage mouse embryos and generation of chimeric mice; screening and analyzing transgenic mcie; use of softwares for genetics and molecular biology (e.g. GCG) and bioimformatics databases.
Honors and Awards
NSF Engineering Research Center Fellowship (1989 - 1991)
Fight for Sight Postdoctoral Fellowship (1993 - 1994)
Knights Templar Eye Foundation Research Grant (1996-1997)
Fight for Sight Grant-in-Aid Research Award (1997-1998)
Publications
References