Born
1964
in Bad Reichenhall (Bavaria), Germany
Parents
entrepreneur/hunter; secretary German armed forces
Citizenship
German
Marital Status
Single
Primary School
1970-74
Grundschule Neustadt (Weinstr.) and Böbingen (Pfalz)
High School
1974-83
State Humanistic Kurfürst-Ruprecht Gymnasium, Neustadt (Weinstr.)
Abitur/Baccalaureat
1983
Avg.: 1.2 on a scale from 1.0 to 6.0 (Top <1%), supported by a governmental stipend from 1980-83
Volontary Service
1982-91
Member of THW (Technisches Hilfwerk), Protection against cathastrophes
Medical School
1983-89
University of Heidelberg (Heidelberg/Mannheim), supported by a governmental stipend from 1983-1989
M.D. Thesis
(Molecular Cell Biology)1986-90
german title: "Klonierung eines genomischen DNA-Fragments mit fur Lamin C codierenden Sequenzen"
Cloning of murine Lamin C gene
Screening of genomic and cDNA libraries (Ehrlich ascites tumor)
Institute of Cell and Tumor Biology (Dir. Prof. W.W. Franke)
German Cancer Research Center Heidelberg
(Prof. D. Werner)
Postdoctoral Training
(Neurobiology)1989-91
Retroviral gene transfer in brain/neural transplants
SV40 LT induction of PNET's (brain tumors)
Establishing of neuronal stem-cell-like tumor cell lines
p53 mutations in nervous system tumors
Institute of Neuropathology
University of Zürich, Switzerland
Department of Pathology
(
Prof. O.D. Wiestler
and
Prof. P. Kleihues, same Department as1996 Nobel prize winner Prof. R.M. Zinkernagel))
(Molecular Genetics)
1991-94
Specific mutation of CD44 gene
CD44 splice-variants in brain tumors
MAb blocking of spontaneous metastases
Analysis of transgenic mice
Institute of Genetics, University of Karlsruhe
(Prof. P. Herrlich)
Approbation
1992
Registration as a Doctor, License to practice Medicine
Journeys/Stipends
1995/6
USA, Greece, Spain, France, Switzerland
Stipend from European Community, Stipend from german DFG for Harvard/MGH, transferred to Stanford University
Postdoctoral Training
(Metastasis Research / Immunology)
1997-99
New metastasis flow chamber model
Rapid arrest of melanoma cells under flow (VCAM-1/alpha-4 integrin)
SDF1 mediated activation of VLA4 / VCAM1 binding
CD44-hyaluronate mediates monocyte rolling
Chemokines, NOD-autoimmune model
Department of Pathology (Immunology)
Stanford University School of Medicine
(supported by DFG stipend and tuition sponsor, Nobel prize candidate for stem cells, Prof. Irving L. Weissman / and Butcher-Lab)
(Metastasis Research)
2000+01
Chemokine receptorsCXCR4 and CCR7 in breast and brain tumors
Inst. of Med. Mikrob.,Immunol. and Inst. of Pathology
Technical University of Munich
(Prof. B. Holzmann/Prof. H.
Wagner and Prof. H. Höfler)
(Chemical Engeneering)
2002
Neurones and Cardiomyocytes in Biosensors
Crystal Quartz resonance analysis and cell adhesion
MEAs (Mikro-Elektrode-Arrays)
Max Planck Institute for Polymer Research
(Prof. W.Knoll / Material Sciences)
(NanoPhysics)
since 2003
Cell adhesion and metastasis on a molecular level on living cells
...with atomic-force microscopy
University of MIAMI,FL (U.S.A.)
(School of Medicine, Department of Physiology and Biophysics)
Scientific Interests
Metastasis, Tumorbiology, Chemokines,Cell Adhesion Receptors, Gene Therapy, Neural-/hematopoetic Stem cells
Other Interests
underwater-photography/snorkeling on Key Biscayne, Cross-country "mountain"-Biking, Advanced Snowboarding, Biotech start-up companies, Extreme-Windsurfing, People, California, Everglades, Munich, Internet, Botanics, Entomolog/mainly butterlflies, Squash, Photography, Diving (Rescue diver/PADI certificate), Sailing/Catamaran (BK certificate)....
Foreign Languages
English, French, Latin (big Latinum), Spanish/Italian (basic)