Zhongqi Zhang, Ph.D.

Selected Publications

1. Zhongqi Zhang, "De Novo Peptide Sequencing Based on a Divide-and-Conquer Algorithm and Peptide Tandem Spectrum Simulation", Anal. Chem. (2004), 76(21), 6374-6383.
2. Zhongqi Zhang, "Prediction of Low-Energy Collision Induced Dissociation Spectra of Peptides", Anal. Chem. (2004), 76(14), 3908-3922.
3. G. Jones, M. Ronk, F. Mori and Z. Zhang, "Disulfide Structure of Alfimeprase - A Recombinant Analog of Fibrolase", Protein Science (2001), 10(6), 1264-1267.
4. Z. Zhang and J. S. McElvain, "De Novo Peptide Sequencing by Two-Dimensional Fragment Correlation Mass Spectrometry", Anal. Chem. (2000), 72(11), 2337-2350.
5. A. G. Marshall, M. R. Emmett, M. A. Freitas, C. L. Hendrickson and Z. Zhang, "Isotopic Amplification, H/D Exchange, and Other Mass Spectrometric Strategies for Characterization of Biomacromolecular Topology and Binding Sites", Mass Spectrometry in Biology and Medicine, Ed. A. L. Burlingame and S. A. Carr (Humana Press, Totowa, NJ, 1999), 31-52.
6. Y. Deng, Z. Zhang and D. L. Smith, "Comparison Of Continuous And Pulsed Labeling Amide Hydrogen Exchange/Mass Spectrometry For Studies Of Protein Dynamics", J. Am. Soc. Mass Spectrom. (1999), 10, 675-684.
7. Z. Zhang and J. S. McElvain, "Optimizing spectroscopic signal-to-noise ratio in analysis of data collected by a chromatographic/spectroscopic system", Anal. Chem. (1999), 71(1), 39-45.
8. Z. Zhang and A. G. Marshall, "Method for gradient elution in micro-flow liquid chromatography", HRC-J. High Resolut. Chromatogr. (1998), 21(5), 291-297.
9. Z. Zhang and A. G. Marshall, "A universal algorithm for fast and automated charge state deconvolution of electrospray mass-to-charge ratio spectra", J. Am. Soc. Mass Spectrom. (1998), 9, 225-233.
10. Z. Zhang, W. Li, T. M. Logan, M. Li and A. G. Marshall, "Human recombinant [C22A] FK506-binding protein amide hydrogen exchange rates from mass spectrometry match and extend those from NMR", Protein Science (1997), 6, 2203-2217.
11. Z. Zhang, W. Li, M. Li, T. M. Logan, S. Guan and A. G. Marshall, "High-order structure and dynamics of FK506-binding protein probed by backbone amide hydrogen/deuterium exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry", Tech. in Protein Chem. VIII (1997).
12. Z. Zhang, S. Guan and A. G. Marshall, "Enhancement of the Effective Resolution of Mass Spectra of High-Mass Biomolecules by Maximum Entropy-Based Deconvolution to Eliminate the Isotope Natural Abundance Distribution", J. Am. Soc. Mass Spectrom.(1997), 8, 659-670.
13. D. L. Smith, Y. Deng and Z. Zhang, "Probing the noncovalent structure of proteins by amide hydrogen exchange and mass spectrometry", J. Mass Spectrom. (1997), 32(2), 135-146.
14. Z. Zhang and D. L. Smith, "Detection of thermal-induced unfolding domains in aldolase by amide hydrogen exchange and mass spectrometry", Protein Science (1996), 5(7), 1282-1289.
15. Z. Zhang, C. B. Post and D. L. Smith, "Amide hydrogen exchange determined by mass spectrometry: Application to rabbit muscle aldolase", Biochemistry, (1996), 35, 779-791.
16. D. L. Smith and Z. Zhang, "Probing the noncovalent structural features of proteins by mass spectrometry [Review]", Mass Spectrom. Reviews (1994), 13, 411-429.
17. D. L. Smith, Z. Zhang and Y. Liu, "Amide hydrogen exchange and mass spectrometry: a probe of high-order structure in proteins", Pure & Appli. Chem., (1994), 66(1), 89-94.
18. Z. Zhang and D. L. Smith, "Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation", Protein Science (1993), 2, 522-531.
19. G. Thevenon-Emeric, J. Kozlowski, Z. Zhang and D. L. Smith, "Determination of amide hydrogen exchange rates in peptides by mass spectrometry", Anal. Chem. (1992), 64, 2456-2458.