The information below was either taken from the official Resident Evil website or is information I learned from playing the games myself. All information, characters, etc. are copyright Capcom.
Some of the information also comes from specific in-game sources (example - Wesker's Report II, XXX Character's Diary, and so on). Most of these sources are noted.

This timeline contains game spoilers. This timeline does not cover all games. It covers only the events leading up to the beginning of the S.T.A.R.S. Alpha team mission at the start of Resident Evil.

Resident Evil/Bio Hazard Timeline
Year/Date Info/Description
1953 Birth of Kenneth J. Sullivan, S.T.A.R.S. Bravo Team Scout. Deceased July 23, 1998. Devoured by zombie inside the Spencer Mansion.
1957 Birth of Enrico Marini, Captain of the S.T.A.R.S. Bravo Team. Killed July 23, 1998 by a single gunshot wound (possibly fired by Barry Burton, under the command of Albert Wesker).
1960 Birth of Barry Burton. Ex S.W.A.T., currently part of the S.T.A.R.S. Alpha Team. Working under threat to his family by Albert Wesker.
1961 Michael Warren, an engineer, moves to Raccoon City and begins work on the city’s cable car system. He eventually becomes mayor.
1963 Birth of Brad Vickers, part of the S.T.A.R.S. Alpha Team. Known as “chickenheart”, he pilots the helicopter (and abandons the team) during a botched team disembark at the Spencer Mansion.
1967 (November 10) Progenitor Virus administered to Jessica and Lisa Trevor, wife and daughter of famed architect, George Trevor. Kidnapped and held in the Spencer Mansion, Jessica eventually dies, Lisa lives. Trevor’s Diary; George Trevor’s aunt becomes ill and is sent to a nearby hospital. Jessica and Lisa intend to visit her.
1969 Birth of Forest Speyer, S.T.A.R.S. Bravo Team sniper and vehicle specialist. Deceased July 23, 1998 on a balcony inside Spencer Mansion. Possibly attacked and killed by crows affected by the T-Virus. Later becomes a zombie.
1970 Estimated “birth” of Alfred and Alexia Ashford, twins in the long line of Ashfords. Their father Alexander (along with Lord Spencer) created the T-Virus. The twins then experimented on Alexander, turning him into the creature known as “Nosferatu”. After the inventin of the T-Veronica Virus, Alexia enters a cryogenic start chamber to mutate and strengthen her powers.
1971 Birth of Joseph Frost, S.T.A.R.S. Bravo Team vehicles specialist, who joined Alpha Team under orders from Albert Wesker. Deceased July 23, 1998 on Spencer Mansion grounds. Devoured by zombified hounds.
1972 The Raccoon City chapter of S.T.A.R.S. (Special Tactics and Rescue Squad) is established.
1973 Birth of Chris Redfield, S.T.A.R.S. Alpha Team member. Dishonorably discharged from the Air Force, Chris is recruited for S.T.A.R.S. by Barry Burton.
1975 Birth of Richard Aiken, S.T.A.R.S. Bravo Team communications specialist. Killed by an unknown entity (possibly zombie dogs) on the Spencer Mansion grouns July 23, 1998

Virus

Year/Date Info/Description
1978 Wesker's Report II; Albert Wesker arrives at the Arkley Laboratories ignoring the Umbrella President and remaining aloof to the other staff. He commences reseach on the Ebola Virus and attempts to created a B.O.W. (Bio Organic Weapon). Wesker first encounters the "woman", a creature who has been constantly experimented on with multiple viral strains since her first injection on November 10, 1967.
1980 Birth of Rebecca Chambers, Bravo Team medic and part time pianist. One day before Alpha Team's arrival in Raccoon Forest, she investigates a mysterious train (game time--Resident Evil 0). Albert Wesker shoots her in the best, but she survies and escapes the mansion (game time--Resident Evil, Resident Evil Director's Cut). Her status is currently active.
1981 Birth of Steve Burnside. An immature but good-hearted child, he is hold on the remote Rockfort island with his father as a prisoner of Umbrella Inc.
1981 (July 27) Wesker's Report II; ten year old Alexia Ashford is given permission to head up Umbrella's Antarctic Research station. Her family's reputation is legendary (her father, Alexander Ashford first discovered the T-Virus), although Ashford's son, Alfred, is useless. Wesker vows to commence research on the laboritories older workers, but Dr. William Birkin is envious of Alexia and isn't mentally capable of helping Wesker. An imprecise Killing Machine named the "Zombie" is created. However, its infection ration isn't perfect. The "woman" still lives, and Wesker is surprised as how resilient she has become
1983 (January 30) Alfred's Diary; Alfred Ashford, inside the secret Antarctic Umbrella base, keeps a diary where he mentions a secret passageway, accesible only by using three family brooches. He cannot retrieves his father's brooch.
1983 (February 17) Alfred's Diary; Alfred manages to secure the brooch and enter the sealed room. He makes a shocking discovery-- His DNA was spliced from a family ancestor and surgate mother; Both Alfred and Alexia are experiments. Angry and jealous that his father chose Alexia (she exhibits genius intelligence, he does not), Alfred is determined to avenge his blundered birth.
1983 (March 3) Alfred's Diary; Alfred and Alexia begin to experiment using the T-Veronica Virus on a "human body" they find -- their father. Alfred worries that the family butler will find out about this macabre experiment.
1983 (April 22) Alfred's Diary; Alexander Ashford is turned into a freakishly mutated being that comes to be known as "Nosferatu", and he is locked away in a secret basement room. Alexia, meanwhile, continues to experiment on herself, and she informs Alfred that she needs to be frozen 15 years before the T-Veronica Virus can consume her. Alfred, now alone, mentally degenerates completely.
1983 Wesker's Report; Wesker hears that Alexia died after injecting herself with the T-Veronica Virus. He can't rely on Alfred to help with research. Wesker begins to wonder why Ozwell Spencer located the laboratory here, especially as Wesker believes other species (both animal and vegetable) could be affected by the virus. He realizes that placing a base in the Antarctic wasn't so crazy after all. The "failure" at the laboratory (the "woman" infected back in 1967) has been forgotten. Wesker's true intentions- that he's been planted in the Umbralla organization by another company- are still secret.
1986 Birth of Sherry Birkin, daughter of Umbrella scientists, Dr. William Birkin and Annette Birkin. Sherry wears a small neck pendant that carries the G-Virus. Albert Wesker's forces may be holding her against her will.
1987 Residents of Raccoon City elect Michael Warren (the engineer who pioneered the town's cable car system) mayor of Raccoon City. Warren holds this position until the town is destroyed; he dies in the nuclear explosion
1988 Wesker's Report II; Wesker can't believe Birkin is bringing life into the world when he works in such a place, especially as work has begun on the Tyrant, a genetically superior soldier. However, very few "test-subjects" could survive with the T-Virus inside them; most turn into zombies. Only 10 people in the United States have the correct DNA. Hearing that Umbrella France has recently started the Nemesis Project, Wesker requests appropriate samples, realizing that a tremendous soldier can now be created. The Nemesis parasite has a short life expectancy outside of the host body, so Wesker resolves to plant the Nemesis parasite into "the woman". The results are surprising-- She devours the parasite and lives. Wesker switches his research and begins to work on the "failure".

Anti-Virus
Year/Date Info/Description
1992 After five years as mayor of Raccoon City, Michael Warren begins to rely heavily on Umbrella's "charitable" donations. The money helps to build a hospital, a public utility works, a munciple building, and helps "keep the public peace".
1993 The newly appointed Raccoon City chief of police, Brian Irons, begins to take bribes from Umbrella, Inc. to ignore the disapearances of locals, Umbrella's "experimental" areas of the city, and other atrocities. Chief Irons becomes more erratic.
1995 (July 31) Wesker's Report II; Wesker returns to Arklay Laboratories after a four year absence. Birkin heads the G-Virus experiment that Wesker begins. The G-Virus continually mutates its host, creating a creature that resurrects itself from the dead. Spencer spends less and less time at the Raccoon facility. A new lead researcher named John arrives, and the experiments on "the woman" begin to turn violent -- She rips the faces off careless researchers and wears them on her hunched back. She is destroyed, but Wesker wonders what Spencer has in store for Umbrella.
1996 While Mayor Warren and Police Chief Irons stonewall any protests, Umbrella, Inc. is permitted to construct the Arklay Laboratories near the old Spencer Mansion, away from the main business district but still within Raccoon City limits.
1997 Barry Burton leaves his job as S.W.A.T. team sergeant to become a full-time member of S.T.A.R.S. Burton recruits Chris Redfield, and both move to Raccoon City to revamp the S.T.A.R.S. team there. ---- Ada Wong, a spy infiltrating the Umbrella organization to gain more information on their viral experiments, manages to become intimate with an Umbrella researcher named John.--- The Raccoon City Police Department moves into the disused Raccoon City Art Gallery. Artwork remains in the building during the move, but many paintings and statues arrive shortly afterward. They belong to Chief Irons.
1998 (April 25) Manager's Diary; A technician is hired to manage Arklay Laboratories and "disposal" facility. The lab is near the mansion, disguised as a factory.
1998 (May 10) Keeper's Diary; The keeper looks after a new specimen, which may be a Chimera. The beast dismembers and disembowels its meat (a wild pig) before eating. --- Secretary's Diary; Chief Irons acquires another disgusting painting; a naked human, being hanged.
1998 (May 12) Keeper's Diary; A T-Virus leak shuts down the Arklay Laboratories basement area. The keeper dons a haz-mat (hazardous materials) suit.
1998 (May 12) Keeper's Diary; The keeper feels "musty" and "itchy" after 24 hours in the haz-mat suit.
1998 (May 13) Keeper's Diary; The keeper goes to the laboratory clinic when his itchy back becomes swollen. He removes his haz-mat suit, they bandage his back. --- Prisoner's Diary; On Rockfort Island, a prisoner complains that his cell "stinks of death." He shares a bunk bed with an "interesting" fellow named Bob.
1998 (May 14) Keeper's Diary; A blister appears on the keeper's foot; he hobbles to the dog pen. Some of the hounds have escaped. --- Manager's Diary; Arklay Laboratories tests a special, but unstable, gas that decomposes living cells.
1998 (May 15) Keeper's Diary; An armed guard prevents the keeper from leaving or making phone calls.

Anti-Virus

Year/Date Info/Description
1998 (May 16) Keeper's Diary; A scientist is shot trying to escape the secured Laboratory. That night, a piece of rotting flesh falls from the keeper's arm. --- Prisoner's Diary; Bob says tht he was the assistant to Alfred Ashford, but was imprisoned over a "tiny little mistake."
1998 (May 17) The T-Virus accidently saturates a laboratory plant in the Arklay Laboratories, creating Plant 42. An angry researcher floods the mansion's lower rooms, freeing sharks infected with the T-Virus.
1998 (May 19) Keeper's Diary; The T-Virus metamorphosis is almost complete. The keeper attacks and eats the guard.
1998 (May 20) A female hiker is found on the bank of the Marble River. The body shows signs of animal laceratins. --- Manager's Diary; Despite possessing a keycard, the manager is accidently locked inside a "treatment room" in the Arklay Laboratories. --- Prisoner's Diary; Military personnel move Bob to a building that people never return from.
1998 (May 21) Plant 42 Report; Umbrella researcher Henry Sarton writes about a mutating plant that attacks by crushing its victims in its vines or by bloodletting with its tendrils. This monster has preyed upon several scientists.
1998 (May 27) The Raccoon Times writes a report on the discovery of the dead hiker. The police think a grizzly bear attacked her.
1998 (June 7) Manager's Diary; Staff members are becoming unruly and will not correctly dispose of experimentations.
1998 (June 8) Researcher's Note; John, a researcher, tells his sweetheart how to correctly exit the Arklay Laboratories. Passcodes are mentioned.
1998 (June 16) The Raccoon Weekly runs a story about strange "dog-like" creatures roaming the mountains near the Spencer Mansion. The paper urges people to try to photograph or capture a specimen.
1998 (July 9) The Raccoon Times; "Mystery in Arklay Mountains" reports that local authorities closed the roads into the wilderness area; they summoned S.T.A.R.S. to help investigate. Grotesque monsters are still in the area, and more families have vanished.
1998 (July 16) Manager's Diary; Bodies in the facility are still being dumped into exterior containers, not burned per instructions. The plant disposal system cannot cope with "demand". They workers feel a little strange, they're taking medicine, but it isn't working.
1998 (July 22) White Umbrella; A clandestine organization gives strict orders on an "X-day." S.T.A.R.S. members are to be lured into a laboratory to battle the mutating experiments. --- Suicide note; A researcher, writing to his wife, details a viral outbreak in Arklay Laboratories. He destroys his colleague with an ornate pistol then hangs himself.
1998 (July 23) Raccoon City television runs a story about 10 families missing in the Arklay Mountains. Human remains have been found in the area. A military police vehicle is discovered in the mountains. Rebecca Chambers reports that corpses of Military Police, plus an unidentified body, are uncovered near the vehicle. Alpha and Bravo S.T.A.R.S. teams are ordered to look for any survivors. The Teams assemble on the eveneing of July 23rd. Bravo Team makes an initial sweep of the lower-lying forested areas.
1998 (July 24) The evil is upon us!


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