Julia Nancy Bailey
Statistical Geneticts, Neuropsychiatric Institute, UCLA School of Medicine

EDUCATION/TRAINING:

INSTITUTION AND LOCATION DEGREE YEAR(s) FIELD OF STUDY

PROFESSIONAL AND RESEARCH EXPERIENCE:
Postdoctoral Fellow, Child and Adolescent Psychiatry, UCLA School of Medicine, 1996-2000.
Research Assistant - Child Study Center, Yale University School of Medicine, 1990-1996.
Research Associate - University of Miami School of Medicine, 1990-1994.
Research Assistant - Lakeshore General Hospital, Pte. Claire, Canada, 1989.
Research Assistant - Biology Dept.- Concordia University, 1986-1988.

TRAINING AND WORKSHOPS:
Linkage Analysis, Columbia University, taught by Y.Ott, PhD
Statistical Analysis for Genetic Epidemiologists (SAGE) taught by R. Elston, PhD
Genetic Analysis of Multifactorial Disease Wellcome Trust Summer School
Genetic Analysis Workshop (GAW), 1992, 1994, 1996, 1998, 2000.

GRANTS AWARDED:
Co-investigator - The Neurobiology and Genetics of Autism
Principal investigator - CAN Research Fellowship. Candiate gene search in autism

COLLABORATIONS:
GENESS - GENetic EpilepsieS Study
The international Molecular Genetic Study of Autism Consortium.

PROFESSIONAL MEMBERSHIPS:
International Society for Genetic Epidemiologists
American Society for Human Genetics
American Association for the Advancement of Science
American Epilepsy Society

PhD DISSERTATION:Bailey, J. N. (1996): Obsessive and compulsive behaviors and risk factors in high functioning pervasive developmental disorder. Ph.D. Thesis, Yale University, New Haven. CT. Advisor: David Pauls, PhD

PUBLICATIONS:

Bai, D, Alonso ME, Bailey JN, Morita R, Median MT, Cordova S, Rasmussen A, Ramos-Peek J, Donnadieu FR, Yamakawa K, Delgado-Escueta AV. Juvenile Myoclonic Epilepsy: Linkage To Chromosome 6p 12-11 In Spanish/Amerind Families. Submitted to the Annals of Neurology.

Suchard, MA, Bailey JN, Elashoff, DA, Sinsheimrer JS. SNPing Away at Candidate Genes. In Press.

Khare L, Stirzheva GD, Bailey JN, Smith M, Smalley SL, Petri Henske E. Possible genotype-phenotype correlation in Tuberous Sclerosis Complex: Identification of a missense mutation in the TSC2 "GAP Domain" in a family with mild disease. In press J Med Genet.

Crawford, LR, Bailey JN, Merriman BL, Kustanovich V, Smalley S, Nelson S. The Characterization and Genotying of single Nucleotide Polymorphisms in coding regions of Brain-expressed autism candidate geneses. Am J Hum Genet 67:4-S134.

Bailey JN, Sinshehimer JS, Assarnow R, McCraken J, Smalley SL. How Broad is the Broader Autistic Phenotype? Almost submitted

Smalley SL, Bailey JN, Crawford L, Nelson SF (1988): Genetic and environmental influences in the development of attention deficit hyperactivity disorder. Am J of Med Genet 81:458. psychiatric genetics

Minassian S, Moison MJ, Sinsheimer JS, Bailey JN, Smalley SL (1999): Testing gene X environment and gene X gene interactions in attention deficit hyperactivity disorder (ADHD) using conditional logistic regression. Mol Psych 4:1-S12

Bailey JN, Asarnow RF, McCracken J, Smalley SL (1998): Additional support for the existence of the broader autistic phenotype. Mol Psych 4:1-S13

Fiddler DJ, Bailey JN, Smalley SL. Macrocephaly in Autism and Other Pervasive Developmental Disorders. Dev Med Child Neurol 2000 Nov;42(11):737-40.

Fiddler DJ, Bailey JN, Smalley SL. Minor Physical Anomalies and Prenatal Complications in Autism. Submitted.

Bailey JN, Suchard MA, Smalley SL, Sinsheimer JS (1999). Search for a Gene by Environment Interaction G X E Hunt. Genet Epidemiol 17:S491-496.

Bailey JN, Ornitz E, Gehricke JG, Gabikiadn P, Russell A, Smalley SL (1999) Independent transmission of Primary Nocturnal Enuresis and Attention Deficit Disorder. Acta Paediatr 88(12):1364-8.

Palmer CGS, Bailey JN, Ramsey C, Cantwell D, Sinsheimer J, Del'Homme M, McGough J, Woodward JA, Asarnow R, Asarnow J, Nelson S, Smalley SL (1999): No evidence of linkage or linkage disequilibrium between DAT1 and attention deficit hyperactivity disorder in a large sample. Psychiatr Genet. 1999 Sep;9(3):157-60

Smalley SL, Bailey JN, Palmer CG, Cantwell DP, McGough JJ, Del'Homme MA, Asarnow JR, Woodward JA, Ramsey C, Nelson SF (1998). Evidence that the dopamine D4 receptor is a susceptibility gene in attention deficit hyperactivity disorder. Mol Psychiatry 3(5):427-30

Bailey JN, Palmer CGS, Ramsey C, Cantwell D, Kim K, Woodward JA, McGough J, Asarnow JA, Asarnow RF, Nelson S, Smalley SL (1997): DRD4 gene and susceptibility to ADHD: Differences in familial and sporadic cases. Am J of Med Genet 74:623.

Bailey JN, Cantwell D, Asarnow J, Smalley SL (1997): Segregation analysis of Attention Deficit Hyperactivity Disorder. Genet Epidemiol 14:518.

Palmer CGS, Bailey JN, Ramsey C, Cantwell D, Del'Homme M, McGough J, Woodward JA, Asarnow R, Asarnow J, Smalley SL, Nelson S (1997): Possible evidence of DAT1 gene by sex interaction in susceptibility to ADHD. Am J of Med Genet 74:630.

McGough J, Nivatpumin P, Bailey JN, Del’Homme M, Asarnow J, Asarnow R, Cantwell D, Smalley S (1997): Psychiatric comorbidity across DSM-IV subtypes in adult ADHD. Presented to the Child and Adolescent Psychiatry meeting, Toronto, October 1997.

Bailey JN, Palmer CGS,Woodward JA, Smalley SL (1997): A multivariate approach to affected sib pair analysis using highly dense molecular maps. Genet Epi. in press.

Pauls DL, Bailey JN, Carter AS, Allen CR, Egeland JA (1995): Complex segregation analyses of Old Order Amish families ascertained through bipolar I individuals. Am J of Med Genet 60:290-297.

Bailey JN, Almasy L (1995): A brute force dicotomization approach to quantative trait linkage analyses. Genet Epi 12:719-722.

Pauls DL, Carter AS, Rooke J, Bailey JN, Egeland JA (1993): Complex segregation analyses of Old Order Amish bipolar pedigrees. Psych Genet 3:143.

Bailey JN, Egeland JA, Ginns EI, Pauls DL (1993): The effects of differential phenocopy rates on linkage analyses. Psych Genet 3:189.

Bailey JN, Pauls DL (1993): The effect of severity dependent ascertainment on risks to first degree relatives. Genet Epi 10(5):143.

Bailey JN, Morton L, Pauls DL (1992): The consequences of inbreeding, maternal and sibling effects in genetic analyses of simulated nuclear families. Am J Hum Genet 51:4.

Keith T, Ginns EI, Egeland JA, Falls K, Allen C, Long RT, Phipps P, Gravious T, Olsson K,Bailey JN, Pauls DL, Paul SM (1991): Systematic search of the genome for markers linked to bipolar affective disorder. Am J Hum Genet 49:346.

Ginns EI, Keith T, Egeland JA, Falls K, Allen C, Long RT, Phipps P, Gravious T, Olsson K, Bailey JN, Pauls DL, Paul SM (1991): Update on the search for DNA markers linked to manic depressive illness in the core and extensions of Old Order Amish pedigree 110. Psych Geneti 2:39.

Consortium Publications

International Molecular Genetic Study of Autism Consortium (1998). A full genome screen for autism with evidence for linkage to a region on chromosome 7q. Hum Mol Genet 7(3):571-8.

Maestrini E, Lai C, Marlow A, Matthews N, Wallace S, Bailey A, Cook E, Weeks, D, Monaco, A, and the International Molecular Genetic Study of Autism (IMGSA) Consortium (1999). Serotonin transporter (5-HTT) and g-Aminobutyric acid receptor subunit b3 (GABRB3) gene polymorphisms are not associated with autism in the IMGSA families. Am J. Med. Genet. (Neuropsychiatr. Genet.) 88:492-496.


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