README.html
May-28-97
Release 4.0
Heladia Salgado, Araceli M. Huerta, Denis Thieffry, and Julio Collado-Vides.
Laboratorio de Biología Computacional
CIFN/UNAM
E-mail: ecoli-t1@cifn.unam.mx.
The files available in this webpage contain the predictions of promoters, of regulatory sites, and operons in the complete genome sequence of E. coli.
A summary of these results is presented as part of the paper: Blattner F.R.; Plunkett III G.; Bloch C.A.; Perna N.T.; Burland V.; Riley M.; Collado-Vides J.; Glasner J.D.; Rode C.K.; Mayhew G.; Gregor J.; Davis N.W.; Kirkpatrick H. A.; Goeden M.A.; Rose D.J.; Mau B.; Shao Y. (1997) "The complete genome sequence of Escherichia coli K-12" Science 277: 1453-1462
The details of the methods used for these predictions will be published in a couple of papers:
Huerta A.M.; Salgado H.; and Collado-Vides J. "Whole Genome promoter prediction in Escherichia coli" (to submit)
Thieffry D.; Salgado H.; Huerta A.M. y Collado-Vides J. (1998) "Prediction of transcription regulatory sites in the complete genome of Escherichia coli" Bioinformatics (in press)
The information on the database used for these predictions is contained in RegulonDB, -see http://www.cifn.unam.mx/Computational_Biology/regulondb/ and the associated publication:
Huerta A.M.; Salgado H.; Thieffry D. y Collado-Vides J. (1998) "RegulonDB: A Database on Transcription Regulation in Escherichia coli" Nucleic Acids Res. 26: 55-60
Name Description Size
Parent Directory E.coli.operons.txt Predicted and known operons in the complete E.coli genome sequence. 424kB E.coli.promoters.txt Promoters predicted in the complete E.coli genome sequence. 1080KB E.coli.sites.txt Regulatory sites predicted on putative regulatory regions of the E.coli genome. 408kB