Fast Facts About Breast Cancer One in eight women will develop breast cancer during her lifetime. Mammograms can detect cancer up to two years before a lump can be felt. Eighty percent of women who develop breast cancer have no family history of the disease. In Arizona, breast cancer is the leading form of cancer among women. An estimated 2,700 women will be diagnosed, and 670 women will die of breast cancer in Arizona this year. An estimated 180,200 new cases of breast cancer will be diagnosed in the United States during 1997, making it the most frequently diagnosed cancer among women. Breast cancer is currently the second leading cause of cancer death in women, with an estimated 44,190 women losing their lives to this disease during 1997-- one woman every 12 minutes. More than 97 percent of women whose breast cancer is found and treated early with no spreading beyond the breast, will survive. Risk Factors Simply getting older and being a woman puts you at risk; 80 percent of breast cancer cases occur in women over age 50 Family history of breast cancer (mother, sister, or daughter with breast cancer or having 2 or more close relatives with breast cancer) Women carrying identified genetic alterations, such as those in BRCA-1 and BRCA-2, may be more susceptible to breast cancer Never had children First childbirth after age 30 Early menstruation (before age 12), late menopause (after age 55) A high fat diet may contribute to risk Women who have had breast cancer face an increased risk of getting breast cancer again Warning Signs A lump or thickening in the breast or under the arm A change in the size or shape of the breast Discharge from the nipple A change in the color or feel of the skin of the breast or nipple area (such as dimpling, puckering or scaliness) Early Detection Guidelines Following these mammography and breast self-exam guidelines could reduce deaths from breast cancer in women over age 50 by as much as 35 percent, and in women in their 40's by 17 percent: Ask for regular screening mammograms every one to two years if you are age 40 or over. Seek expert medical advice about whether you should begin screening before age 40 and the frequency of screening if you are a woman with higher than average risk of breast cancer. Ask for yearly breast exams by a doctor or nurse. Perform monthly breast self-exams. At any age if you develop a lump in your breast, it should be examined by your doctor and may require a mammogram. Risks Among Minority Women Minority women (African-American, Hispanic and Native American) have a higher risk of dying from breast cancer than any other cancer. Breast cancer in minority women is often diagnosed at more advanced stages. Unfortunately, few minority women know about and take advantage of mammography. However, the news is improving. In 1987, only 31 percent of African-American women 40 and older had ever had a screening mammogram to detect breast cancer, compared with 67 percent in 1992. Among African-American women 40 and older who reported having had a mammogram within the year, in 1987 that figure was only 14 percent, compared to 32 percent in 1992. Although Hispanics are reported to have lower incidence of breast cancer than Anglo-Americans, they tend to be diagnosed at more advanced stages. National data available for 1992 shows that 38 percent of Hispanic women ages 40 and older have had a mammogram within the past year and 70 percent report having had at least one mammogram ever. This improvement in utilization, up from 13 percent and 28 percent respectively in 1987, is largely due to outreach education efforts. A strong sense of family values and a matriarchal society characterize Hispanic culture. Younger women are better informed and more open to health education, but they are highly influenced by their mothers and grandmothers. An appeal to Hispanic women might help them consider the consequences to their families if they, their mothers or grandmothers should be lost to cancer. While there is less data available for Native American women, overall cancer survival rates for Native Americans are lower than the Anglo population. Like the Hispanic population, Native Americans differ culturally and linguistically from the majority of Americans. These differences, combined with lack of access to healthcare, impact of culture and use of traditional healers are possible explanations of these findings. Breast Self-Exam (BSE) Breasts come in all shapes and sizes just as women do. Breast self-exam is intended to help you learn what is normal for you. BSE is done once a month so that you become familiar with the usual appearance and feel of your own breasts. Familiarity makes it easier to notice any changes in your breasts from month to month. Early discovery of a change is the whole idea behind BSE. If you discover anything unusual, such as a lump, discharge from the nipple, or dimpling or puckering of the skin, you should see your doctor at once. Remember, eight out of 10 breast lumps are not cancer. The human breasts are paired subcutaneous organs composed of glandular breast tissue, fat, and fibrous tissue. As an endocrine target organ, breasts are sensitive to monthly hormonal changes. Before menstruation, estrogen and progesterone increase the size of the glandular tissue, the vascularity and the amount of water in the breast, making good breast examinations difficult. All of these changes regress after menstruation. The ideal time for a breast examination is two to three days after the end of your menstrual period, when the breast achieves its minimal volume, and true changes are easier to detect. A woman who no longer has periods may find it helpful to pick a particular day, such as the first of the month, to remind herself that it is time to do BSE. Breast Lumps Women frequently consult their doctors about suspected breast lumps. In women under 40, breast lumps are usually benign. Most lesions seen at this age are "fibroadenomas" (smooth, round masses with a clearly defined edge), "cysts" (round, mobile, often tender masses that may appear suddenly), or simply "prominent breast tissue" (common in younger women with a small amount of breast fat, which makes the glandular tissue easily palpable). Fibroadenomas occur twice as often in African-American women as in others. If a breast lump is detected on physical examination, a small needle may be inserted into the lump to determine if it is solid or cystic. If it is solid, removal under local anesthesia on an out-patient basis is all that is indicated. Removal is recommended because the mass will not disappear but will grow slowly, and confirming the lump is benign provides peace of mind to the patient. If aspiration with a needle reveals a greenish-bluish fluid, this most likely is a benign cyst. If the mass turns out to be cystic and completely disappears, careful follow-up, often including a mammogram (especially if the patient is over 40), is all that is indicated. These cysts may be multiple and may reappear in the future. Breast lumps in women over 50 always are considered potentially malignant until proven otherwise. Mammography Mammography allows physicians to detect small and early changes that may be suspicious. It can detect breast cancer up to two years before you or your doctor can feel a lump. Mammography is an X-ray of the breast from the top (craniocaudal view) and the side (lateral view). The amount of radiation from a mammogram is very small. Women under age 40 should discuss the role of screening mammography with their doctors, taking into account family history and other risk factors. Mammography in younger women is less accurate. It usually reveals only dense breast tissue that may mask an underlying tumor. Mammography is more accurate in women over 50 whose glandular breast tissue has become atrophic. As women age, glandular tissue disappears, becomes atrophic and is replaced by fat. It is recommended that women over age 40 request a mammogram every one to two years. Comparison between successive mammograms is necessary. If you have had a mammogram done elsewhere, it is helpful to bring it with you when a new one is ordered. If an abnormality is seen on the mammogram, you may require further evaluation and biopsy. Two-thirds of women do not follow recommended guidelines for mammography. It is estimated that cancer deaths would decline in women over age 50 by at least 35 percent if women got mammograms as recommended.