Trim fat from brisket. Combine chili powder, garlic powder, celery seed, and pepper; rub evenly over meat. Place meat in 1 3 1/2, 4 or 5 qt. crock pot.
For sauce combine ketchup, chili sauce, brown sugar, vinegar, Worchestershire sauce, liquid smoke and dry mustard. Pour over brisket.
Cover and cook on low for 8-10 hours or on high for 4-5 hours.
Remove meat from crockpot. Cut into thin slices across the grain. Skim fat off juices in cooker; serve juices with meat.
Recipe submitted by florentine on 7/17/00