Season One
Starring: | Kristanna Loken .............................................. Jane Vasco |
| Alaina Huffman ................................... Maureen Bowers ( - 12) |
| Noah Danby .................................................. Connor King |
| Stephen Lobo ......................................... Dr. Seth Carpenter |
| Sean Owen Roberts .......................................... Riley Jensen |
And: | Rob Stewart ............................................... Andre McBride |
Based upon the Painkiller Jane series of comic books by Jimmy Palmiotti & Joe Quesada |