Employment opportunities
The following list of employment opportunities
is provided to facilitate the selection of interested individuals.
Nevertheless, exceptionally qualified scientists and professionals
are encouraged to submit an employment application at any
time. All individuals seeking employment must meet the
eligibility requirements of the Office of Human Resources
of Columbia University.
The Colleen Giblin Laboratories
are located at the Neurological Institute of New York, a
14-floor facility that houses the first modern academic
department of Neurology established in America. The Neurological
Institute has been renovated in 2001, including the construction
of a magnetic resonance research facility in the subbasement,
and is located at the Columbia Presbyterian Medical Center
campus of Columbia University and New York Presbyterian
Hospital, one of the major biomedical complexes in the United
States and the largest in New York City. Institutions on
campus include the College of Physicians & Surgeons
and associated research centers, The Presbyterian Hospital,
The Milstein Hospital building, the Children’s Hospital
of New York, the New York State Psychiatric Institute and
the biomedical technology park of Columbia University.
The Colleen Giblin Laboratories, a spacious facility overlooking
the Hudson River, include state of the art work areas, offices,
meeting and library space and equipment and are linked by
a computer network to the scientific and clinical resources
of the campus. Subscription to many on-line journals is
provided free of charge by the Medical Center library and
there are gymnastic and childcare facilities on campus.
Transportation to the Morningside campus of Columbia University
is free of charge.
The Laboratories include
facilities for the performance of:
DNA cloning, mutation screening
and mutagenesis
RNA extraction and synthesis
Fluorescence in situ hybridization
Transgenic mice
Cell and oocyte culture
and injection
Protein characterization
and binding
Biochemistry
Oocyte voltage clamp
Patch clamp
Spectrophotometry
Scientific photography
Networked computing, digital
image processing and scientific presentation
Journal library
Applications should
be e-mailed, when feasible, to:
giblinlabs@neuro.columbia.edu
Or, alternatively, mailed
in triplicate to:
Dr. Darryl De Vivo
Colleen Giblin Laboratories
Neurological Institute
710 West 168th Street
New York, NY 10032
Laboratory technician,
molecular biology
Requires two or more years
of experience with recombinant DNA, including bacterial
culture, plasmid preparation, mutagenesis, RNA isolation
and synthesis, transfection and sequence analysis.
Senior laboratory
technician, tissue culture
Involves the expansion
and maintenance of patient cell lines and samples for research
purposes. All aspects of tissue culture, including mammalian
cell transfection, shipping and receiving of samples, and
management of the tissue culture laboratory budget must
be performed. Requires extensive experience in a similar
position.
Postdoctoral research
scientist
Molecular basis of cerebral
energy utilization and failure
The position is designed
to provide a scientist with the training necessary to lead
an independent scientific career in the field of molecular
biology and biochemistry of metabolism applied to disease.
The focus is on conditions that cause neurological disorders
using the methods of molecular genetics, biochemistry, functional
and metabolic brain imaging and of transgenic animal models
and experimental therapeutics. Extensive access to and
familiarity with clinical material is encouraged as a resource
for scientific investigation.
Formal experience, such
as that obtained during a doctorate’s degree in molecular
biology and/or biochemistry, is required.
Postdoctoral research
scientist
Molecular excitability
disorders
The successful candidate
will become most proficient in the fields of ion channel
structure and function and of ion channel disorders or channelopathies.
A first aspect of this research focuses on the identification
of novel ion channel mutants and interacting proteins involved
in human disease, such as those affecting muscle and neural
tissues. A second line of investigation is centered on
the relationships between ion channel structure and function,
and is aimed to elucidate the fundamental mechanisms of
channel operation in normal and diseased states and to provide
the basis for the understanding of pharmacological drug
action on ion channels. Contact with research patients
is offered, as a means of broadening research interests.
Experience must include
voltage and patch clamp. Knowledge of molecular biology
is desired.
