Genes, Morphogenesis, Evolution: Life and ALife Aspects
Boolean Network Models
Rapid progress in the deciphering of the genomes of humans and other
organisms has led to discovery of hundreds of genes whose sole function
is to control and regulate the activity of other genes.These genes comprise
the genetic networks, which can be considered as a complex feedback web
of genes which turn each other on and off and ultimately control the expression
of structural genes as their final target.
Genetic networks has been used to model biological systems for several
decades. For computational reasons the only model system that has yielded
insights into the overall behaviour of large genetic networks (up to 100,000
genes) is the Boolean network model introduced
by Kauffman almost thirty years ago.
Modelling of genetic networks as a Boolean networks:
Models:
References
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