Genes, Morphogenesis, Evolution: Life and ALife Aspects

Drosophila Segmentation Mechanisms:

Reverse and Obverse of The Problem

---

Nowadays, molecular mechanisms of a fruit fly embryo segmentation belong apparently to one of the most investigated subject.

Drosophila Segmentation Mechanisms

Drosophila Segmentation Genetic Networks

Links:

STEPHEN J. SMALL - even-skipped gene pattern

Prof. Christiane Nusslein-Volhard' department:

• Localization of bcd RNA in the Drosophila embryo
• Determination of dorsoventral polarity in the Drosophila embryo

A vast of experimental data obtained in this field, in turn, stimulate extensive theoretical considerations of principles and schemes of early body segmentation in invertebrates and vertebrates.

Axel Hunding seems use the most powerful hardware - parallel computer Cray for dynamical modeling of the fruit fly early segmentation pattern appearance:

"…a model that describes the regulatory effect of one gene on another, as well as the diffusion of gene products between cell nuclei…"

• Model for cooperative control of positional information in Drosophila by bicoid and maternal hunchback, J. Reinitz, E. Mjolsness, and D.H. Sharp.
• Reinitz, J., Mjolsness, E., and Sharp, D.H. (1995) Model for cooperative control of positional information in Drosophila by bicoid and maternal hunchback. J. Exp. Zool. 271: 47-56.

"Current work is directed at extending the model to include pair-rule genes." JOHN REINITZ

Reinitz, J. and Sharp, D.H. (1995) Mechanism of eve stripe formation. Mech. Dev. 49: 133-158.

---

This page hosted by Get your own Free Homepage