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 Feline Urologic Syndrome
   
Definition of FUS: Contributing factors: Signs and symptoms: Prevention and medical treatment:
FUS is any disease of the lower urinary tract which includes the bladder and urethra.  Most cats with FUS develop mineral crystals in their urine.  These crystals combined with a mucoid-like protein secreted by the urethra often form mucous plugs that block the urethra causing the cat either dribble urine, or unable to urinate at all.    

Inflammation of the membrane that lines the bladder is called cystitis.   

Inflammation of the urethra is called urethritis.   

Cats with FUS often have both cystitis and urethritis.

Diets containing high levels of alkaline magnesium salts.   

Inadequate water consumption.    

Physical inactivity.   

Intentional urine retention (which may occur if a cat holds his urine in order to void outside, or habitually waits until his litter box is cleaned before he'll use it).   

Stress.   



Other factors suggested but not proven to play a role in the development of FUS include genetic  immune system defects, viruses, and less likely, bacteria.   
   
 
Staining to urinate.   

Blood in the urine.   

Urine with a strong ammonia odor.   

Concentrated urine.   

Frequent trips to the litter box with only small amounts of urine voided.   

"Camping out" in the litter box in a squatting position.   

Crying while urinating.   

Loss of usual litter-box habits such as urinating small amounts of urine in unusual places.   

Note:  If you are suspicious that your cat is acting constipated because he's straining in the litter box, please suspect FUS and get him checked. 

Appropriate diet such as cat foods made to prevent FUS:  Iam's, Science Diet, Nutra Max, Pro-Plan, Nutra Nuggets, and Diamond all have acidic pH, low magnesium formulas.    

Prescription diets such as Hill's, Feline Maintenance, or C/D.   

Urine acidifiers (methionine, an amino acid; and ammonium chloride, a salt) are available in palpable paste form that the cat can lick off his paw.  Never give urine acidifiers to a cat already on a prescription diet.  It can make the cat's blood too acidic and cause a life-threatening  metabolic acidosis.    
   
 

 
This is an extreme emergency.  Go directly to your vet or emergency animal hospital for treatment.    
Constant straining with no urine production.    
Extreme discomfort and pain.    
Howling.   
Palpable, over distended bladder.  The bladder will feel firm and very large, like a baseball.   
Lethargy, depression, vomiting, dehydration, anorexia, coma, death. 
Emergent treatment for a blocked cat is:   
  • Urinary catheterization (passing a narrow tube through the urethra and into the bladder) to relieve the obstruction and drain the urine. 
  • IV fluids and antibiotics may be given. 
  • Recurrence can be prevented in the majority of cases by feeding an acidic, magnesium restricted, diet. 
If blockage re-occurs, after appropriate medical treatment then the cat  may be a candidate for perineal urethrostomy surgery.  This procedure is for male cats only and involves castration and permanently opening the urethra past the constricted area.  It is a last resort. 
 

    The Morris Foundation discovered that the urine produced by cats fed strictly an all mice diet, had the all the  proper levels of electrolytes and was pH balanced to perfection.

 
References: 
Feline Practice, The Journal of Feline Medicine and Surgery for the Practitioner, Colloquium on Urology, Sept/Dec 1997, Vol.25, Numbers Five/Six 
"Understanding Feline Urologic Syndrome," Amy D. Shojai 
"Urinary Obstruction in Cats," Cornell Feline Health Center, Cornell University, College of Veterinary Medicine, Ithaca, NY, USA 
The Cat Diseases and Clinical Management, Vol. 1, Robert G. Sherding, DVM, 1989 
  
 
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